Procalcitonin and community-acquired pneumonia (CAP) in children

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The role of procalcitonin (PCT) as a biomarker for sepsis inadults is well documented, while its role in infections affectingneonatal children remains controversial. Among these infections,Community-Acquired pneumonia (CAP) has been studied extensively, becauseit's the second cause of death in children in developing countries, andone of the most frequent causes of hospitalization in industrializedcountries.The PubMed database and the Cochrane Library were used to search for thefollowing keywords: CAP, procalcitonin, children. Thirteen articles werestudied to determine the role of PCT in CAP management, specifically itsusefulness for distinguishing pneumococcal infections from viral andunknown infections, for predicting severity and the correct antibiotictreatment. This paper focuses on the studies performed to identify thebest inflammatory biomarker for CAP management.Although there is an increase in studies confirming the usefulness of PCTin CAP management in children, further studies are needed to have betterunderstanding of its role for pediatric CAP management.
Original languageEnglish
Pages (from-to)215-218
Number of pages4
JournalClinica Chimica Acta
Volume451
Publication statusPublished - 2015

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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