Prevalence of metabolic syndrome: a comparative analysis in an unselected sample of mediterranean subjects.

Manfredi Rizzo, Salvatore Novo, Egle Corrado, Giuseppina Novo, Filippo Ferrara, Cinzia Nugara, Francesca Macaione, Giuseppa Caccamo, Giuseppe Coppola, Sonia Dell'Oglio

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

AbstractAIM:The metabolic syndrome (MS) is associated with increased cardiovascular and cerebrovascular risk. This study aimed to compare the difference of the three established diagnostic criteria of MS, developed by Adult Treatment Panel III (ATP III), American Heart Association (AHA) and National Heart Lung and Blood Institute (NHLBI), and International Diabetes Federation (IDF), with regard to the prevalence of the syndrome and the ability to correctly identify individuals with cardiovascular or cerebrovascular disease or subclinical atherosclerosis.METHODS:We studied 947 consecutive patients underwent clinical evaluation between the 1997-2002. The project design included a medical assessment, biochemical analyses and the ecocolordoppler examination of carotid arteries.RESULTS:The MS prevalence was 37% in ATPIII subjects, 36% in AHA/NHLBI subjects and 43% in IDF subjects. Excluding patients with diabetes (N.=259), the MS prevalence ranged from 32% (ATPIII and AHA/NHLBI subjects) and 40% (IDF subjects). By most criteria, MS-positive subjects had significant incidence of carotid atherosclerosis (P<0.05) and cardiovascular events (P<0.05) than MS-negative subjects, but not cerebrovascular events. Finally, patients with MS had higher serum levels of fibrinogen (P<0.04).CONCLUSION:Subclinical atherosclerosis and cardiovascular events were increased in presence of the MS, irrespective of the several definitions.
Original languageEnglish
Pages (from-to)572-578
Number of pages7
JournalINTERNATIONAL ANGIOLOGY
Volume31
Publication statusPublished - 2012

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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