Prevalence of cardiovascular risk factors and coronary artery events between immigrant patients from south-east asia and south italian patients with acute coronary syndrome

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Abstract

Aims: The aim of this study is trying to better define determinants of the greatestrisk of coronary events in Asian patients compared with south Italian group. In everypatient we evaluate the incidence of risk factors, the extent of coronary artery disease and the incidence of major cardiovascular adverse events (MACE) after followup (average of 36 months).Methods and Results: In this study, 56 patients with Acute coronary syndrome (ACS)from south-east Asia were recruited, originating mainly from Bangladesh, India andSri Lanka, hospitalized between 2013 and 2018. In the study, we compared the characteristics of the Asian population with a control group made up of 56 Sicilianpatients who were also hospitalized for ACS in the same period. The demographic,clinical and procedural characteristics were analyzed by consulting an electronicarchive. The incidence of MACE was assessed by 36-month follow-up, analyzing thenamely death, re-ima, angina and possible death from non-cardiovascular events.The group of Asian patients (88% of males and 13% of females) have an age of 48years whereas the control group of Italian patients (82% of males and 18% of females)have an average age of 58. In the assessment of risk factors, we observed a significant difference in incidence regarding obesity, in fact only 5% of Asians are obesedespite 88% of Italian patients. It is also possible to highlight a higher incidence oftype 2 diabetes mellitus in Asians, an expression of a greater predisposition to insulinresistance. Remarkable is the difference between smokers, more Italian than theAsians (77% vs 36%). We also focused our attention on coronary angiography, studyingvessels with critical stenoses (occlusion of the lumen greater than 70%) and comparing the data of the two populations. With reference to coronary stenoses, it is notedthat in the group of Asian patients, the multiple lesions are 36%, while in Italianpatients the multiple lesions result to be 50%. Finally, we compared the incidence ofmajor cardiovascular adverse events (MACE) with a mean follow-up of 36 monthscomparing the two populations. In Asian patients, 75% had new episodes of angina,4% had a heart attack, 17% died from a cardiovascular cause, while mortality due to‘other’ causes was not confirmed. In the group of Italian patients only 8% of patientshad angina, while none had a re-heart attack or death.Conclusion: From our study we can see an important prognostic difference betweenAsian patients and Italian patients in a medium follow up. Therefore, it is advisableto pay attention to the different impact of cardiovascular risk factors and to theneed to ensure surveillance of the health status of minorities present in the Europecountry, to guarantee a better adherence to therapy and positively change the burden of cardiovascular disease
Original languageEnglish
Number of pages1
JournalEUROPEAN HEART JOURNAL SUPPLEMENTS
Publication statusPublished - 2020

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