Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen

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Abstract

Several new diorganotin(IV) and triorganotin(IV) complexes with 4-amino-3- (4-chloro phenyl)]-butanoic acid ( = Baclofen) have been synthesized and their structure investigated both in the solid state and in solution phase through spectroscopic methods (FT-IR, Mössbauer, 1H and 13C NMR). According to experimental analytical data, the stoichiometry of the complexes has been proposed as R2SnBac2 and R3SnBac, respectively for diorganotin(IV) and triorganotin(IV) baclofen complexes. (Baclofen = HBac; R = Me, Bu, Ph).
Original languageEnglish
Pages (from-to)139-152
Number of pages14
JournalATTI DELLA ACCADEMIA DI SCIENZE, LETTERE E ARTI DI PALERMO, PARTE PRIMA: SCIENZE
VolumeSERIE QUINTA, VOL.XXIV (TOMO I: Scienze)
Publication statusPublished - 2008

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