On the Interaction between 1D Materials and Living Cells

Yana Aleeva, Bruno Giuseppe Pignataro, Giuseppe Domenico Arrabito, Clara Chiappara, Yana Aleeva, Vittorio Ferrara, Giuseppe Prestopino, Clara Chiappara

Research output: Contribution to journalArticle

Abstract

One-dimensional (1D) materials allow for cutting-edge applications in biology, such as single-cell bioelectronics investigations, stimulation of the cellular membrane or the cytosol, cellular capture, tissue regeneration, antibacterial action, traction force investigation, and cellular lysis among others. The extraordinary development of this research field in the last ten years has been promoted by the possibility to engineer new classes of biointerfaces that integrate 1D materials as tools to trigger reconfigurable stimuli/probes at the sub-cellular resolution, mimicking the in vivo protein fibres organization of the extracellular matrix. After a brief overview of the theoretical models relevant for a quantitative description of the 1D material/cell interface, this work offers an unprecedented review of 1D nano- and microscale materials (inorganic, organic, biomolecular) explored so far in this vibrant research field, highlighting their emerging biological applications. The correlation between each 1D material chemistry and the resulting biological response is investigated, allowing to emphasize the advantages and the issues that each class presents. Finally, current challenges and future perspectives are discussed.
Original languageEnglish
Pages (from-to)40-
Number of pages41
JournalJournal of Functional Biomaterials
Volume11
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering

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    Aleeva, Y., Pignataro, B. G., Arrabito, G. D., Chiappara, C., Aleeva, Y., Ferrara, V., Prestopino, G., & Chiappara, C. (2020). On the Interaction between 1D Materials and Living Cells. Journal of Functional Biomaterials, 11, 40-.