MR imaging technique for the diagnosis of pituitary iron overload in patients with transfusion-dependent beta-thalassemia major

Massimo Midiri, Gianvincenzo Sparacia, Gianvincenzo Sparacia, Alberto Iaia, Aurelia Banco, Massimo Midiri

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

To identify the optimal MR imaging technique for diagnosing pituitary iron overload, we compared spin-echo and gradient-echo MR imaging with measurements of pituitary T2 relaxation times in 30 patients with secondary hemochromatosis due to transfusion-dependent beta-thalassemia major and in 10 healthy volunteers. We found that the optimal MR imaging technique to evaluate pituitary iron overload is the gradient-echo T2*-weighted technique, as it best demonstrated signal reduction in the anterior lobe of the pituitary gland.
Original languageEnglish
Pages (from-to)1905-7-
Number of pages3
JournalAJNR, AMERICAN JOURNAL OF NEURORADIOLOGY
Volume19
Publication statusPublished - 1998

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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