To identify the optimal MR imaging technique for diagnosing pituitary iron overload, we compared spin-echo and gradient-echo MR imaging with measurements of pituitary T2 relaxation times in 30 patients with secondary hemochromatosis due to transfusion-dependent beta-thalassemia major and in 10 healthy volunteers. We found that the optimal MR imaging technique to evaluate pituitary iron overload is the gradient-echo T2*-weighted technique, as it best demonstrated signal reduction in the anterior lobe of the pituitary gland.
|Number of pages||3|
|Journal||AJNR, AMERICAN JOURNAL OF NEURORADIOLOGY|
|Publication status||Published - 1998|
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
Midiri, M., Sparacia, G., Sparacia, G., Iaia, A., Banco, A., & Midiri, M. (1998). MR imaging technique for the diagnosis of pituitary iron overload in patients with transfusion-dependent beta-thalassemia major. AJNR, AMERICAN JOURNAL OF NEURORADIOLOGY, 19, 1905-7-.