Monitoraggio dell’adeguatezza prescrittiva dell’albumina per uso terapeutico presso una realtà ospedaliera della Provincia di Palermo.

Claudio Costantino, Maria Grazia Laura Marsala

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[automatically translated] Objectives The Health Department Hospital Buccheri La Ferla - Fatebenefratelli, in collaboration with the Hospital Pharmacy, analyzed the data on the annual consumption of albumin, in order to verify the appropriateness of prescriptions based on the guidelines of the scientific literature. Methods From 2009 has been prepared standardized forms of albumin request aimed at rationalizing their use. In each module shows the personal details, serum albumin, total proteinaemia, the therapeutic indication and the number of bottles required for each patient. They have All data were entered into a database created with the software EpiInfo 3.5.1 and analyzed using the R statistical software were analyzed application forms for the years 2009 and 2010 The qualitative variables were summarized as absolute and relative frequencies and quantitative variables were represented as mean ± standard deviation. Results In the two years were received in the service of Hospital Pharmacy 905 albumin requests, of which 345 (38%) during 2009, and 560 (62%) during 2010. A total of albumin required vials were 2,673 in 2009 and 2,223 in 2010 . the average of vials prescribed for single request is significantly lower than in 2010 (7.7 ± 2.9) than in 2009 (4.0 ± 2.5) (p <0.0001). The 53.2% of the requests come from the surgical area departments and in particular 41.9% by the UO of General Surgery. Furthermore, it is evident that the average number of vials for single request of albumin of OO.UU. the surgical area (6.1 ± 3, 3) it is significantly greater than that of OO.UU. the medical area (4.6 ± 2.9) (p <0.0001). The main therapeutic indication stated in the examined modules is represented by malnutrition (28.7%), understood as a condition of hypoalbuminemia or imposing diarrhea / non domabile with diet. 23.1% in the prescription is related to cancer cachexia, while in 19.3% is not indicated the reasons for the prescription. In particular, the failure to therapeutic indication is higher in 2009 (26.4%) than in 2010 (15%). The conclusions of the Hospital albumin consumption Buccheri La Ferla - Fatebenefratelli show a downward trend in 2010 over the previous year, since due to the recent rationalization process of the prescription of albumin in clinical practice.
Original languageItalian
Number of pages2
Publication statusPublished - 2011

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