Management of large dorsal diffuse plexiform neurofibroma

Salvatore D'Arpa, Adriana Cordova, Francesco Moschella, Adriana Tuttolomondo, Carlo Melloni

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Abstract Neurofibromas are considered one of the hallmarksigns of neurofibromatosis type 1(NF1). Diffuse plexiformneurofibroma is a congenital NF1-associated tumor, characterizedby overgrowth and interference with function of theaffected area. The rich vascular plexus associated with neurofibromas,together with their infiltrative pattern, makes themdifficult to eradicate. Complications of neurofibromas are rarebut include malignant transformation and potentially lifethreateninghemorrhages. The use of the term “giant” to definea neurofibroma is controversial because there is no clearconsensus and descriptions are limited to few case reports.We report a case of a large dorsal diffuse plexiform neurofibromaresponsible for significant worsening of a patient’squality of life. These features make us believe that the masscan be defined as “giant.” Comprehensive perioperative management,including arterial embolization of the feeding vesselsand stabilization of the patient’s conditions, is required toperform a safe surgical procedure in such a complicated case.
Original languageEnglish
Pages (from-to)349-352
Number of pages4
JournalEuropean Journal of Plastic Surgery
Volume37
Publication statusPublished - 2014

All Science Journal Classification (ASJC) codes

  • Surgery

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