Low-loading asymmetric organocatalysis

Research output: Contribution to journalArticle

235 Citations (Scopus)

Abstract

Asymmetric organocatalysis is now recognized as the third pillar of asymmetric synthesis.Recent years have witnessed increasing interest towards the use of highly active andstereoselective organocatalysts. This critical review documents the advances in the development ofchiral organocatalysts which are systematically used in r3 mol% loading in all the sub-areas of the field, namely aminocatalysis, Brønsted acids and bases, Lewis acids and bases, hydrogen bond-mediated catalysis, phase transfer and N-heterocyclic carbene catalyses
Original languageEnglish
Pages (from-to)2406-2447
Number of pages42
JournalChemical Society Reviews
Volume41
Publication statusPublished - 2012

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Lewis Bases
Lewis Acids
Catalysis
Hydrogen bonds
Acids
carbene

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Low-loading asymmetric organocatalysis. / Giacalone, Francesco; Gruttadauria, Michelangelo; Noto, Renato; Agrigento, Paola.

In: Chemical Society Reviews, Vol. 41, 2012, p. 2406-2447.

Research output: Contribution to journalArticle

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