LIVER HAEMANGIOMAS UNDETERMINED AT GREY-SCALE ULTRASOUND: CONTRAST-ENHANCEMENT PATTERNS WITH SONOVUE AND PULSE-INVERSION US

Tommaso Vincenzo Bartolotta, Roberto Lagalla, Massimo Midiri, Massimo Galia, Tommaso Vincenzo Bartolotta, Emilio Quaia, Filippo Cademartiri, Michele Bertolotto

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Abstract

The objective of this study was to describe the spectrum of contrast-enhancement patterns of hepatic haemangiomas undetermined at grey-scale ultrasound (US) onSonoVue-enhanced pulse-inversion (PI) US. Twenty patients (11 women, nine men)with 35 haemangiomas (size range: 1-7 cm; mean: 3.1 cm) undetermined at baseline US underwent PI at low M.I. (0.05-0.08) after i.v. injection of SonoVue. Allhaemangiomas were confirmed by typical helical computed tomography (CT) and/ormagnetic resonance imaging (MRI) findings. US examinations were videotaped andthen reviewed by two experienced radiologists blinded to the final diagnosis.Readers evaluated by consensus the baseline echogenicity and the dynamicenhancement pattern of each lesion, in comparison with adjacent liver parenchyma.After administration of SonoVue, 31/35 (88%) haemangiomas showed peripheralhyperechoic nodules in the arterial phase, followed by progressive centripetalfill-in, which was complete in 25/35 cases and incomplete in 6/35 cases. Threeout of 35 (9%) haemangiomas showed rapid and complete fill-in in the arterialphase, which persisted in the portal and delayed phases. Finally, 1/35haemangiomas (3%) showed a rim of arterial contrast enhancement with progressive and complete centripetal fill-in in portal-venous and delayed phases. Inconclusion, PI after the administration of SonoVue enabled the depiction oftypical contrast-enhancement patterns in haemangiomas undetermined at baselineUS.
Original languageEnglish
Pages (from-to)685-693
Number of pages9
JournalEuropean Radiology
Volume15 (4)
Publication statusPublished - 2005

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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