Marcello Romeo, Francesco Cappello, Giovanni Tomasello, Nardone, Guarracino, Compare, Sanduzzi Zamparelli, Gerardo Nardone, Rocco

Research output: Book/ReportOther report


[automatically translated] Diverticular disease is a disease quite common in Western populations. E 'estimated that 30-40% of patients undergoing imaging procedures on the digestive system present diverticula of the colon. These, in 75% of cases are completely asymptomatic. diverticulosis appears closely related to lifestyle and the typical eating habits of Western countries. as a result of this geographic preference, the Anglo-Saxon authors define this condition "a disease of western civilization". Diverticulosis occurs usually in adults, the disease trend increases proportionally with age; nevertheless, in recent years we have observed a trend invesrione and involvement of younger age groups. in this reference book are addressed by the authors, not of the same scientific-academic backgrounds, those notions of morphological order, pathophysiological and clinical disease. Among the causal elements of diverticular disease is the first the role of diet low in fiber connected to constipation and obesity. congenital weakness of colic walls seems to exert a clear role concausale. The crucial problem related to the presence of diverticula is represented by mucosal inflammation of the diverticulum (diverticulitis). this in turn can lead to a whole series of complications that require immediate hospitalization and emergency surgery. diverticular inflammation correlates to specific modifications of the environment such as endolumiinale ' increased pressure, the low proportion of fibers and especially the alterations / quantitative microbial flora resident, known as microbiota. the latest scientific findings show that the microbiota aterazione - called dysbiosis - is the trigger event responsible for the activation of the lymphatic system, the intestinal mucosal -GALT (Gut Associated Limphoyd tissue). This triggers the sequence of events of immune order and biochemical evidence that support with 2forza and vigor "mucosal inflammation: the diverticulum becomes inflamed and diverticulitis appears. The maintenance of the state of the intestinal eubiosis, thus becomes a necessary condition to maintain proper and tropism mucosal health. These pathophysiological etio-order acquisitions allow you to open new application scenarios for a glimpse, in the darkness visible, highly biocompatible therapeutic protocolii and free of side effects, designed to prevent diverticulitis. The use of bacteria - called probiotics - essential for the welfare and bowel function, helps maintain the correct balance microbial commensal, which protects the mucosa by inflammatory events. we also know that chronic inflammation-recurring mucosal implements the risk of cancer of the intestinal tract with the active participation of enteropathogenic flora. The active commitment to maintaining that state of intestinal eubiosis, together with the smooth introduction of fiber in the diet, so is the priority message, the end point,
Original languageItalian
Number of pages67
ISBN (Print)978-88-98731-02-2
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Ageing
  • Geriatrics and Gerontology

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