Inositol supplementation and IVF outcome:preliminary data

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Myo-Inositol (MI) is involved in several aspects ofhuman reproduction. Elevated concentrations ofmyo-inositol in human follicular fluids, in fact, seemto play a positive role in follicular maturity, since torepresent a possible marker of good oocyte quality.Nevertheless its positive role in PCOS patients is aconsequence of a defect in the insulin signaling (inositol-containing phosphoglycan mediators) pathwaythat seems to be implicated in the pathogenesis of insulinresistance.The aim of this study was to analyze the effect ofmyo-inositol supplementation to “standard” therapyin PCOS women and in “poor responders”, submittedto In Vitro Fecundation (IVF) cycles.In particular, we have investigated its influence onovarian response to hormonal stimulation and onoocytes quality. Preliminary results of our study, anyway,appear in contrast with results of previous studies;supplementation with MI, in fact, do not seem toimprove the response neither in PCOS patients nor inpoor responders.
Original languageEnglish
Number of pages7
JournalITALIAN JOURNAL OF GYNAECOLOGY & OBSTETRICS
Volume24: N.1
Publication statusPublished - 2012

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Fingerprint Dive into the research topics of 'Inositol supplementation and IVF outcome:preliminary data'. Together they form a unique fingerprint.

Cite this