Inclusion complexes of cyclomaltooligosaccharides (cyclodextrins) with melatonin in solid phase

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15 Citations (Scopus)


Fourier transform infrared spectrometry (FT-IR) and X-Ray diffraction (XRD) investigations were carried out on MLT plus α-, β- and γ-CD physical mixtures and lyophilized or crystalline MLT/α-, β-, γ-CD complexes. Inclusion complexes formation between MLT and cyclodextrins in solid phase has been emphasized by the significant differences between IR and XRD spectra of physical mixtures with respect to those of the complexes. The structure of MLT CDs complexes in the solid state as well as the biochemical and pharmaceutical implications are discussed.
Original languageEnglish
Pages (from-to)118-130
Number of pages13
Publication statusPublished - 2005

All Science Journal Classification (ASJC) codes

  • Organic Chemistry


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