Hyaluronic acid-based two-stage medical therapy to unfold the aged face: The centrifugal approach

Salvatore D'Arpa, John Rogers, Carlo Di Gregorio, John Rogers

Research output: Contribution to journalArticlepeer-review


Background: Facial aging is a multifactorial process characterized by structural changes to the dermis and ligaments, lipoatrophy in the fat pads and hypodermis, remodeling of the bony skeleton, change in muscle tonicity and tissue descent. Aims: The purpose of this study is to evaluate the efficacy of a hyaluronic acid-based treatment for the aging face that addresses all its causes in a caudal to cranial and medial to lateral direction: the centrifugal technique. Methods: Between March 2015 and January 2018, 187 patients were treated with a high G’ hyaluronic acid in two sessions, one/two weeks apart, to improve signs of facial aging, starting from the lower centrofacial area and progressing laterally and cranially. Results were assessed using a Global Aesthetic Improvement Scale (GAIS) judging pre- and post-treatment (32 weeks) pictures. Results: The technique effectively treated the aging face. The investigator and all patients evaluated the results improved or very much improved and agreed that the results were very natural looking. Conclusion: Use of a systematic centrifugal technique to address the signs of facial aging resulted in significant and long-lasting improvement, as judged by the investigator and high patient acceptance and satisfaction.
Original languageEnglish
Number of pages6
JournalJournal of Cosmetic Dermatology
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Dermatology


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