Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry

Gaetano Giammona; Fabio Salvatore Palumbo; Giovanna Pitarresi

Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry

Gaetano Giammona, Fabio Salvatore Palumbo, Giovanna Pitarresi

Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche

Research output: Contribution to conference › Other › peer-review

Abstract

Conclusion: HA-g-PDLLA hydrogel is suitable to coat a prosthesis remaining adherent to it and distributing itself in the bone cavity. The hydrogel has been proven effective in a rabbit model of highly contaminated implant. In vivo studies have demonstrated how the intraoperative coating of implants with DAC is safe and feasible. HA-EDA-MA hydrogel is able to protect PEP from alteration during storage and it seems a good candidate for a potential once-daily oral formulation in the treatment of celiac disease.

Original language	English
Number of pages	0
Publication status	Published - 2016

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title = "Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry",

abstract = "Conclusion: HA-g-PDLLA hydrogel is suitable to coat a prosthesis remaining adherent to it and distributing itself in the bone cavity. The hydrogel has been proven effective in a rabbit model of highly contaminated implant. In vivo studies have demonstrated how the intraoperative coating of implants with DAC is safe and feasible. HA-EDA-MA hydrogel is able to protect PEP from alteration during storage and it seems a good candidate for a potential once-daily oral formulation in the treatment of celiac disease.",

author = "Gaetano Giammona and Palumbo, {Fabio Salvatore} and Giovanna Pitarresi",

year = "2016",

language = "English",

}

TY - CONF

T1 - Hyaluronic acid based hydrogels for antibiotics and enzymes release: from academic research to industry

AU - Giammona, Gaetano

AU - Palumbo, Fabio Salvatore

AU - Pitarresi, Giovanna

PY - 2016

Y1 - 2016

N2 - Conclusion: HA-g-PDLLA hydrogel is suitable to coat a prosthesis remaining adherent to it and distributing itself in the bone cavity. The hydrogel has been proven effective in a rabbit model of highly contaminated implant. In vivo studies have demonstrated how the intraoperative coating of implants with DAC is safe and feasible. HA-EDA-MA hydrogel is able to protect PEP from alteration during storage and it seems a good candidate for a potential once-daily oral formulation in the treatment of celiac disease.

AB - Conclusion: HA-g-PDLLA hydrogel is suitable to coat a prosthesis remaining adherent to it and distributing itself in the bone cavity. The hydrogel has been proven effective in a rabbit model of highly contaminated implant. In vivo studies have demonstrated how the intraoperative coating of implants with DAC is safe and feasible. HA-EDA-MA hydrogel is able to protect PEP from alteration during storage and it seems a good candidate for a potential once-daily oral formulation in the treatment of celiac disease.

UR - http://hdl.handle.net/10447/207179

M3 - Other

ER -