High-energy radiation processing,a smart approach to obtain PVP-graft-AA nanogels

Maria Antonietta Sabatino, Giuseppe Spadaro, Clelia Dispenza, Natascia Grimaldi, Sabina Alessi, Maria Luisa Bondì, Dispenza, Kaluska, Przybytniak, Bulone

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


Poly(N-vinylpyrrolidone)-grafted-acrylic acid biocompatible nanogels(NGs)were prepared using an exiting industrial type electron accelerator and setups,starting from semi-dilute aqueous solutions of acommercial PVP and the acrylic acid monomer. As a result, NGs witht unable size and structure can beobtained quantitatively. Sterility was also imparted at the integrated dose absorbed.The chemicalstructure of the NGs produced was confirmed through Fourier Transformer Infrared Spectroscopy(FT-IR).The molecular and physico-chemical properties of NGs,such as the hydrodynamic dimensions andsurface charge densities,for various polymer and monomer concentrations in the irradiated solutions,are discussed here.
Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalRadiation Physics and Chemistry
Publication statusPublished - 2014

All Science Journal Classification (ASJC) codes

  • Radiation

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