Graphene Oxide Carboxymethylcellulose Nanocomposite for Dressing Materials

Alessandro Presentato, Rosa Alduina, Maria Luisa Saladino, Roberto Scaffaro, Patrizia Cancemi, Marta Markowska, Magdalena Wawrzyńska, Dariusz Biały, Mariusz Hasiak, Dariusz Hreniak, Clara Carmone

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Abstract

Sore, infected wounds are a major clinical issue, and there is thus an urgent need for novel biomaterials as multifunctional constituents for dressings. A set of biocomposites was prepared by solvent casting using different concentrations of carboxymethylcellulose (CMC) and exfoliated graphene oxide (Exf-GO) as a filler. Exf-GO was first obtained by the strong oxidation and exfoliation of graphite. The structural, morphological and mechanical properties of the composites (CMCx/Exf-GO) were evaluated, and the obtained composites were homogenous, transparent and brownish in color. The results confirmed that Exf-GO may be homogeneously dispersed in CMC. It was found that the composite has an inhibitory activity against the Gram-positive Staphylococcus aureus, but not against Gram-negative Pseudomonas aeruginosa. At the same time, it does not exhibit any cytotoxic effect on normal fibroblasts.
Original languageEnglish
Pages (from-to)1980-
Number of pages14
JournalMaterials
Volume13
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

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    Presentato, A., Alduina, R., Saladino, M. L., Scaffaro, R., Cancemi, P., Markowska, M., Wawrzyńska, M., Biały, D., Hasiak, M., Hreniak, D., & Carmone, C. (2020). Graphene Oxide Carboxymethylcellulose Nanocomposite for Dressing Materials. Materials, 13, 1980-.