Forty-slice MDCT enteroclysis: evaluation after oral administration of isotonic solution in Crohn's disease

Marcello De Maria, Massimo Galia, Massimo Midiri, Tommaso Vincenzo Bartolotta, Roberto Lagalla, Adele Taibbi, Lo Re, Runza, Tommaso Vincenzo Bartolotta, Massimo Galia, Roberto Lagalla, Massimo Midiri, Marcello De Maria, Giuseppe Runza

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Abstract

Objective. The aim of this study was to evaluate the accuracy of multidetector computed tomography (MDCT) enteroclysis after oral hyperhydration with isotonic solution in detecting bowel wall alterations in patients with Crohn’s disease. Materials and methods. Twenty-eight patients with a diagnosis of Crohn’s disease established by ileocolonoscopy and histology were enrolled in the study; 15 patients with negative ileocolonoscopy served as controls. In all cases, MDCT enteroclysis was performed after oral administration of 2,000 ml of isotonic solution and intravenous administration of N-butylscopolamine. Axial, isotropic multiplanar and volume-rendered reconstructions were used to evaluate bowel wall thickness, ulceration, contrast enhancement, extraparietal involvement and possible complications. Results. MDCT enteroclysis identified the typical signs of Crohn’s disease in 26 patients (92.8%), with sensitivity of 92.8%, specificity of 100%, positive predictive value 100% and negative predictive value 75%.Conclusions. MDCT enteroclysis after oral hyperhydration with isotonic solution showed a high level of accuracy in detecting small bowel changes in patients with Crohn’s disease. It can be considered a safe and effective alternative to conventional radiography and small-bowel spiral computed tomography enema, especially in patients who refuse nasojejunal intubation.
Original languageEnglish
Pages (from-to)787-797
Number of pages11
JournalLA RADIOLOGIA MEDICA
Volume112
Publication statusPublished - 2007

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

De Maria, M., Galia, M., Midiri, M., Bartolotta, T. V., Lagalla, R., Taibbi, A., Lo Re, Runza, Bartolotta, T. V., Galia, M., Lagalla, R., Midiri, M., De Maria, M., & Runza, G. (2007). Forty-slice MDCT enteroclysis: evaluation after oral administration of isotonic solution in Crohn's disease. LA RADIOLOGIA MEDICA, 112, 787-797.