Failed hypospadias in paediatric patients

Enrico De Grazia, Marcello Cimador, Waifro Rigamonti, Santiago Vallasciani, Marco Castagnetti, Gianantonio Manzoni

Research output: Contribution to journalArticle

27 Citations (Scopus)


Failed hypospadias refers to any hypospadias repair that leads to complications or causes patient dissatisfaction. The complication rate after hypospadias repairs ranges from 5-70%, but the actual incidence of failed hypospadias is unknown as complications can become apparent many years after surgery and series with lifelong follow-up data do not exist. Moreover, little is known about uncomplicated repairs that fail in terms of patient satisfaction. Risk factors for complications include factors related to the hypospadias (severity of the condition and characteristics of the urethral plate), the patient (age at surgery, endocrine environment, and wound healing impairment), the surgeon (technique selection and surgeon expertise), and the procedure (technical details and postoperative management). The most important factors for preventing complications are surgeon expertise (number of cases treated per year), interposition of a barrier layer between the urethroplasty and the skin, and postoperative urinary drainage. Major complications associated with failed hypospadias include residual curvature, healing complications (preputial dehiscence, glans dehiscence, fistula formation, and urethral breakdown), urethral obstruction (meatal stenosis, urethral stricture, and functional obstruction), urethral diverticula, hairy urethra, and penile skin deficiency
Original languageEnglish
Pages (from-to)657-666
Number of pages10
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Urology

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    De Grazia, E., Cimador, M., Rigamonti, W., Vallasciani, S., Castagnetti, M., & Manzoni, G. (2013). Failed hypospadias in paediatric patients. NATURE REVIEWS. UROLOGY, 10, 657-666.