Endoscopic sclerotherapy for hemostasis of acute esophageal variceal bleeding.

Giuseppe Di Buono, Giorgio Romano, Gaspare Gulotta, Antonino Agrusa, Daniela Chianetta, Giovanni De Vita, Giuseppe Amato, Giuseppe Frazzetta, Vincenzo Sorce

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction. Currently the most widely used methods for endoscopic control of esophageal varices bleeding are sclerotherapy and rubber band ligation. Although the superiority of band ligation (BL) over endoscopic sclerotherapy (SCL) for the secondary prophylaxis of variceal hemorrhage has been proven, the best approach for acute bleeding remains controversial. Patients and methods. We performed a retrospective study between January 2005 and May 2013. We selected 104 patients with gastrointestinal hemorrhage from rupture of esophageal varices treated with endoscopic sclerotherapy. The sclerosing agent used was 1% polidocanol in 89 cases, butyl-cyanoacrylate in 8 cases and sodium tetradecylsulfate in 4 cases. In 3 cases had not been carried sclerosis because it was not possible to identify the bleeding site. Results. Among the 101 patients who underwent endoscopic sclerotherapy 4 presented re-bleeding within 12 hours from first treatment. Other 10 patients (9.9%) presented re-bleeding within a 5-days period. The most frequent complication was ulceration, observed in 4 cases (3.8%). There was only one case of perforation treated conservatively. Conclusions. The general improvement in the results of the treatment of variceal acute bleeding might be attributed to better clinical management of these patients. In literature no consensus exists regarding the preferred endoscopic treatment. To date, there is no single method applicable to all patients with bleeding esophageal varices, but sclerotherapy is considered effective, safe and repeatable in experienced hands.
Original languageEnglish
Pages (from-to)61-64
Number of pages4
JournalIL GIORNALE DI CHIRURGIA
Volume35
Publication statusPublished - 2014

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Endoscopic Hemostasis
Sclerotherapy
Hemorrhage
Esophageal and Gastric Varices
Ligation
Sclerosing Solutions
Cyanoacrylates
Gastrointestinal Hemorrhage
Rubber
Sclerosis
Rupture
Therapeutics
Retrospective Studies
Sodium

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Surgery

Cite this

Endoscopic sclerotherapy for hemostasis of acute esophageal variceal bleeding. / Di Buono, Giuseppe; Romano, Giorgio; Gulotta, Gaspare; Agrusa, Antonino; Chianetta, Daniela; De Vita, Giovanni; Amato, Giuseppe; Frazzetta, Giuseppe; Sorce, Vincenzo.

In: IL GIORNALE DI CHIRURGIA, Vol. 35, 2014, p. 61-64.

Research output: Contribution to journalArticle

Di Buono, Giuseppe ; Romano, Giorgio ; Gulotta, Gaspare ; Agrusa, Antonino ; Chianetta, Daniela ; De Vita, Giovanni ; Amato, Giuseppe ; Frazzetta, Giuseppe ; Sorce, Vincenzo. / Endoscopic sclerotherapy for hemostasis of acute esophageal variceal bleeding. In: IL GIORNALE DI CHIRURGIA. 2014 ; Vol. 35. pp. 61-64.
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abstract = "Introduction. Currently the most widely used methods for endoscopic control of esophageal varices bleeding are sclerotherapy and rubber band ligation. Although the superiority of band ligation (BL) over endoscopic sclerotherapy (SCL) for the secondary prophylaxis of variceal hemorrhage has been proven, the best approach for acute bleeding remains controversial. Patients and methods. We performed a retrospective study between January 2005 and May 2013. We selected 104 patients with gastrointestinal hemorrhage from rupture of esophageal varices treated with endoscopic sclerotherapy. The sclerosing agent used was 1{\%} polidocanol in 89 cases, butyl-cyanoacrylate in 8 cases and sodium tetradecylsulfate in 4 cases. In 3 cases had not been carried sclerosis because it was not possible to identify the bleeding site. Results. Among the 101 patients who underwent endoscopic sclerotherapy 4 presented re-bleeding within 12 hours from first treatment. Other 10 patients (9.9{\%}) presented re-bleeding within a 5-days period. The most frequent complication was ulceration, observed in 4 cases (3.8{\%}). There was only one case of perforation treated conservatively. Conclusions. The general improvement in the results of the treatment of variceal acute bleeding might be attributed to better clinical management of these patients. In literature no consensus exists regarding the preferred endoscopic treatment. To date, there is no single method applicable to all patients with bleeding esophageal varices, but sclerotherapy is considered effective, safe and repeatable in experienced hands.",
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T1 - Endoscopic sclerotherapy for hemostasis of acute esophageal variceal bleeding.

AU - Di Buono, Giuseppe

AU - Romano, Giorgio

AU - Gulotta, Gaspare

AU - Agrusa, Antonino

AU - Chianetta, Daniela

AU - De Vita, Giovanni

AU - Amato, Giuseppe

AU - Frazzetta, Giuseppe

AU - Sorce, Vincenzo

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N2 - Introduction. Currently the most widely used methods for endoscopic control of esophageal varices bleeding are sclerotherapy and rubber band ligation. Although the superiority of band ligation (BL) over endoscopic sclerotherapy (SCL) for the secondary prophylaxis of variceal hemorrhage has been proven, the best approach for acute bleeding remains controversial. Patients and methods. We performed a retrospective study between January 2005 and May 2013. We selected 104 patients with gastrointestinal hemorrhage from rupture of esophageal varices treated with endoscopic sclerotherapy. The sclerosing agent used was 1% polidocanol in 89 cases, butyl-cyanoacrylate in 8 cases and sodium tetradecylsulfate in 4 cases. In 3 cases had not been carried sclerosis because it was not possible to identify the bleeding site. Results. Among the 101 patients who underwent endoscopic sclerotherapy 4 presented re-bleeding within 12 hours from first treatment. Other 10 patients (9.9%) presented re-bleeding within a 5-days period. The most frequent complication was ulceration, observed in 4 cases (3.8%). There was only one case of perforation treated conservatively. Conclusions. The general improvement in the results of the treatment of variceal acute bleeding might be attributed to better clinical management of these patients. In literature no consensus exists regarding the preferred endoscopic treatment. To date, there is no single method applicable to all patients with bleeding esophageal varices, but sclerotherapy is considered effective, safe and repeatable in experienced hands.

AB - Introduction. Currently the most widely used methods for endoscopic control of esophageal varices bleeding are sclerotherapy and rubber band ligation. Although the superiority of band ligation (BL) over endoscopic sclerotherapy (SCL) for the secondary prophylaxis of variceal hemorrhage has been proven, the best approach for acute bleeding remains controversial. Patients and methods. We performed a retrospective study between January 2005 and May 2013. We selected 104 patients with gastrointestinal hemorrhage from rupture of esophageal varices treated with endoscopic sclerotherapy. The sclerosing agent used was 1% polidocanol in 89 cases, butyl-cyanoacrylate in 8 cases and sodium tetradecylsulfate in 4 cases. In 3 cases had not been carried sclerosis because it was not possible to identify the bleeding site. Results. Among the 101 patients who underwent endoscopic sclerotherapy 4 presented re-bleeding within 12 hours from first treatment. Other 10 patients (9.9%) presented re-bleeding within a 5-days period. The most frequent complication was ulceration, observed in 4 cases (3.8%). There was only one case of perforation treated conservatively. Conclusions. The general improvement in the results of the treatment of variceal acute bleeding might be attributed to better clinical management of these patients. In literature no consensus exists regarding the preferred endoscopic treatment. To date, there is no single method applicable to all patients with bleeding esophageal varices, but sclerotherapy is considered effective, safe and repeatable in experienced hands.

KW - endoscopic sclerotherapy

KW - esophageal variceal bleeding

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