Efficacy of a fasting‐mimicking diet in functional therapy for depression: A randomised controlled pilot trial

Giuseppe Maniaci, Mario Giuseppe Mirisola, Daniele La Barbera, Manfredi Rizzo, Laura Ferraro, Roberto Citarrella, Caterina La Cascia, Valter Longo, Alessandra Giammanco, Roberta Chianetta, Roberta Di Peri, Simonetta Montana, Stefania Larcan, Yuri Christian Mannella

Research output: Contribution to journalArticle

Abstract

Objective: This randomized controlled trial examined the efficacy of adding a fasting‐mimicking diet to a structured psychotherapy protocol for treating depression.Design: Of 20 patients with depression, 10 were randomly assigned to psychotherapy and dieting (i.e., experimental group) and the other 10 to psychotherapy only (i.e., control group). Patients in both groups received20 individual sessions of functional therapy along with nutrition consultation. Patients in the control group were instructed to maintain their usual daily diets. Results: Both treatments were effective in reducing depression as well as increasing self‐esteem and quality of life. The experimental group showed improved self‐esteem and psychological quality of life as well as a reduction in their mean body mass index, in comparison to the control group.Conclusions: The study revealed initial evidence of the efficacy of combining psychotherapy with a fasting‐mimicking diet to treat depression and its correlates
Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalJournal of Clinical Psychology
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Psychology

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