Efficacy and safety of clarithromycin as treatment for Mediterranean spotted fever in children: a randomized controlled trial

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Abstract

Fifty-one children with Mediterranean spotted fever (MSF) were randomized to receive either clarithromycin, 15 mg/kg/day orally in 2 divided doses, or chloramphenicol, 50 mg/kg/day orally in 4 divided doses, for 7 days. Mean time to defervescence was 36.7 h in the clarithromycin group and 47.1 h in the chloramphenicol group (P=.047). Clarithromycin could be an acceptable therapeutic alternative to chloramphenicol and to tetracyclines for children aged <8 years with MSF
Original languageEnglish
Pages (from-to)409-411
Number of pages3
JournalClinical Infectious Diseases
Volume33
Publication statusPublished - 2001

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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