The chemical composition of eight Tunisian Rosmarinus officinalis L. populations (A-H) from different bioclimatic areas has been examined by gas chromatography (GC) and GC-mass spectrometry. The essential oils are characterised by high amounts of oxygenated monoterpenes (58.2-71.7%) followed by monoterpene hydrocabons (15.1-26.7%). 1,8-Cineole, camphor, Î±-pinene and borneol are the main representative components. The antioxidant activity was investigated by 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), ferric reducing ability power assay and Î²-carotene bleaching test. Samples showed antiradical activity by inhibiting DPPH radical with IC50 values ranging from 375.3 to 592.8 g mL- 1for samples F and A, respectively. Sample A also showed the most promising activity in Î²-carotene bleaching test (IC50 of 31.9 g mL- 1). The essential oils were also screened for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity. Sample G showed the highest activity against AChE (IC50 of 64.7 g mL- 1) while sample D (IC50 of 29.5 g mL- 1) exhibited the most potent activity against BChE.
|Number of pages||10|
|Journal||Natural Product Research|
|Publication status||Published - 2015|
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Plant Science
- Organic Chemistry
Bruno, M., Kchouk, M. E., Pugliese, A., Ben Jemia, M., Tundis, R., Menichini, F., Senatore, F., & Loizzo, M. R. (2015). Effect of bioclimatic area on the composition and bioactivity of Tunisian Rosmarinus officinalis essential oils. Natural Product Research, 29, 213-222.