Effect of bioclimatic area on the composition and bioactivity of Tunisian Rosmarinus officinalis essential oils

Maurizio Bruno, Mohamed Elyes Kchouk, Alessandro Pugliese, Mariem Ben Jemia, Rosa Tundis, Francesco Menichini, Felice Senatore, Monica Rosa Loizzo

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The chemical composition of eight Tunisian Rosmarinus officinalis L. populations (A-H) from different bioclimatic areas has been examined by gas chromatography (GC) and GC-mass spectrometry. The essential oils are characterised by high amounts of oxygenated monoterpenes (58.2-71.7%) followed by monoterpene hydrocabons (15.1-26.7%). 1,8-Cineole, camphor, α-pinene and borneol are the main representative components. The antioxidant activity was investigated by 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), ferric reducing ability power assay and β-carotene bleaching test. Samples showed antiradical activity by inhibiting DPPH radical with IC50 values ranging from 375.3 to 592.8 g mL- 1for samples F and A, respectively. Sample A also showed the most promising activity in β-carotene bleaching test (IC50 of 31.9 g mL- 1). The essential oils were also screened for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity. Sample G showed the highest activity against AChE (IC50 of 64.7 g mL- 1) while sample D (IC50 of 29.5 g mL- 1) exhibited the most potent activity against BChE.
Original languageEnglish
Pages (from-to)213-222
Number of pages10
JournalNatural Product Research
Volume29
Publication statusPublished - 2015

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

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  • Cite this

    Bruno, M., Kchouk, M. E., Pugliese, A., Ben Jemia, M., Tundis, R., Menichini, F., Senatore, F., & Loizzo, M. R. (2015). Effect of bioclimatic area on the composition and bioactivity of Tunisian Rosmarinus officinalis essential oils. Natural Product Research, 29, 213-222.