DUODENAL ADENOCARCINOMA: A CASE REPORT

Giorgio Romano, Gaspare Gulotta, Giuseppe Di Buono, Antonino Agrusa, Dumitraşcu, Simona Dima, Bouaru, Martiniuc, Scarlat, Popescu, Cezar Stroescu, Daniela Chianetta, Giovanni De Vita, Giuseppe Frazzetta

Research output: Contribution to conferenceOther

Abstract

Objective: Cancers of the small intestine are rare pathologies. They occur with vague and unspecific symptoms and causemany problems in differential diagnosis.Methods: A 64-years-old man, smoker, suffered inappetence, nausea and vomit over about 20 days until the presence ofmelena led to his admission to our hospital. His history included diabetes mellitus and moderate alcohol intake. The objectiveexamination showed a hard-inelastic swelling in epi-mesogastric region. Laboratory data showed an increase of leukocytesand elevated level of CA 19-9. Esophagogastroduodenoscopy showed a duodenal vegetans neoformation, subjected toexamination biopsy and bacterial culture. Computed tomography scans showed a voluminous duodenal mass without safeplans of cleavage with the head of the pancreas. The biopsy results were not decisive for the presence of necrotic tissue. Themicrobiological culture was positive for Candida Glabrata mimicking an advanced mycotic abscess. Laparotomy revealed apalpable hard mass in duodenum. Cephalic duodenopancreatectomy was performed.Results: Postoperative period was regular. The patient resume eating during the sixth postoperative day and was discharged ingood conditions. The final histological diagnosis was papillary moderately differentiated adenocarcinoma with expansivegrowth in duodenal wall. There was no lymph node involvement or distant organ metastasis.Conclusions: The duodenal tumors are rare pathologies. There is association with familial adenomatous polyposis, Cronhdisease, alcohol abuse, smoking, peptic ulcer. Diagnosis is based on endoscopic and imaging techniques. The mainprognostic factors are tumor stage, lymph node involvement and metastasis. When is possible we perform a radical approachreserving palliative treatment for advanced neoplasm.
Original languageEnglish
Pages37-37
Number of pages1
Publication statusPublished - 2013

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Adenocarcinoma
Lymph Nodes
Pathology
Neoplasm Metastasis
Digestive System Endoscopy
Intestinal Neoplasms
Candida glabrata
Biopsy
Neoplasms
Adenomatous Polyposis Coli
Pancreaticoduodenectomy
Peptic Ulcer
Palliative Care
Duodenum
Postoperative Period
Laparotomy
Abscess
Nausea
Alcoholism
Small Intestine

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Romano, G., Gulotta, G., Di Buono, G., Agrusa, A., Dumitraşcu, Dima, S., ... Frazzetta, G. (2013). DUODENAL ADENOCARCINOMA: A CASE REPORT. 37-37.

DUODENAL ADENOCARCINOMA: A CASE REPORT. / Romano, Giorgio; Gulotta, Gaspare; Di Buono, Giuseppe; Agrusa, Antonino; Dumitraşcu; Dima, Simona; Bouaru; Martiniuc; Scarlat; Popescu; Stroescu, Cezar; Chianetta, Daniela; De Vita, Giovanni; Frazzetta, Giuseppe.

2013. 37-37.

Research output: Contribution to conferenceOther

Romano, G, Gulotta, G, Di Buono, G, Agrusa, A, Dumitraşcu, Dima, S, Bouaru, Martiniuc, Scarlat, Popescu, Stroescu, C, Chianetta, D, De Vita, G & Frazzetta, G 2013, 'DUODENAL ADENOCARCINOMA: A CASE REPORT', pp. 37-37.
Romano, Giorgio ; Gulotta, Gaspare ; Di Buono, Giuseppe ; Agrusa, Antonino ; Dumitraşcu ; Dima, Simona ; Bouaru ; Martiniuc ; Scarlat ; Popescu ; Stroescu, Cezar ; Chianetta, Daniela ; De Vita, Giovanni ; Frazzetta, Giuseppe. / DUODENAL ADENOCARCINOMA: A CASE REPORT. 1 p.
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abstract = "Objective: Cancers of the small intestine are rare pathologies. They occur with vague and unspecific symptoms and causemany problems in differential diagnosis.Methods: A 64-years-old man, smoker, suffered inappetence, nausea and vomit over about 20 days until the presence ofmelena led to his admission to our hospital. His history included diabetes mellitus and moderate alcohol intake. The objectiveexamination showed a hard-inelastic swelling in epi-mesogastric region. Laboratory data showed an increase of leukocytesand elevated level of CA 19-9. Esophagogastroduodenoscopy showed a duodenal vegetans neoformation, subjected toexamination biopsy and bacterial culture. Computed tomography scans showed a voluminous duodenal mass without safeplans of cleavage with the head of the pancreas. The biopsy results were not decisive for the presence of necrotic tissue. Themicrobiological culture was positive for Candida Glabrata mimicking an advanced mycotic abscess. Laparotomy revealed apalpable hard mass in duodenum. Cephalic duodenopancreatectomy was performed.Results: Postoperative period was regular. The patient resume eating during the sixth postoperative day and was discharged ingood conditions. The final histological diagnosis was papillary moderately differentiated adenocarcinoma with expansivegrowth in duodenal wall. There was no lymph node involvement or distant organ metastasis.Conclusions: The duodenal tumors are rare pathologies. There is association with familial adenomatous polyposis, Cronhdisease, alcohol abuse, smoking, peptic ulcer. Diagnosis is based on endoscopic and imaging techniques. The mainprognostic factors are tumor stage, lymph node involvement and metastasis. When is possible we perform a radical approachreserving palliative treatment for advanced neoplasm.",
author = "Giorgio Romano and Gaspare Gulotta and {Di Buono}, Giuseppe and Antonino Agrusa and Dumitraşcu and Simona Dima and Bouaru and Martiniuc and Scarlat and Popescu and Cezar Stroescu and Daniela Chianetta and {De Vita}, Giovanni and Giuseppe Frazzetta",
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T1 - DUODENAL ADENOCARCINOMA: A CASE REPORT

AU - Romano, Giorgio

AU - Gulotta, Gaspare

AU - Di Buono, Giuseppe

AU - Agrusa, Antonino

AU - Dumitraşcu, null

AU - Dima, Simona

AU - Bouaru, null

AU - Martiniuc, null

AU - Scarlat, null

AU - Popescu, null

AU - Stroescu, Cezar

AU - Chianetta, Daniela

AU - De Vita, Giovanni

AU - Frazzetta, Giuseppe

PY - 2013

Y1 - 2013

N2 - Objective: Cancers of the small intestine are rare pathologies. They occur with vague and unspecific symptoms and causemany problems in differential diagnosis.Methods: A 64-years-old man, smoker, suffered inappetence, nausea and vomit over about 20 days until the presence ofmelena led to his admission to our hospital. His history included diabetes mellitus and moderate alcohol intake. The objectiveexamination showed a hard-inelastic swelling in epi-mesogastric region. Laboratory data showed an increase of leukocytesand elevated level of CA 19-9. Esophagogastroduodenoscopy showed a duodenal vegetans neoformation, subjected toexamination biopsy and bacterial culture. Computed tomography scans showed a voluminous duodenal mass without safeplans of cleavage with the head of the pancreas. The biopsy results were not decisive for the presence of necrotic tissue. Themicrobiological culture was positive for Candida Glabrata mimicking an advanced mycotic abscess. Laparotomy revealed apalpable hard mass in duodenum. Cephalic duodenopancreatectomy was performed.Results: Postoperative period was regular. The patient resume eating during the sixth postoperative day and was discharged ingood conditions. The final histological diagnosis was papillary moderately differentiated adenocarcinoma with expansivegrowth in duodenal wall. There was no lymph node involvement or distant organ metastasis.Conclusions: The duodenal tumors are rare pathologies. There is association with familial adenomatous polyposis, Cronhdisease, alcohol abuse, smoking, peptic ulcer. Diagnosis is based on endoscopic and imaging techniques. The mainprognostic factors are tumor stage, lymph node involvement and metastasis. When is possible we perform a radical approachreserving palliative treatment for advanced neoplasm.

AB - Objective: Cancers of the small intestine are rare pathologies. They occur with vague and unspecific symptoms and causemany problems in differential diagnosis.Methods: A 64-years-old man, smoker, suffered inappetence, nausea and vomit over about 20 days until the presence ofmelena led to his admission to our hospital. His history included diabetes mellitus and moderate alcohol intake. The objectiveexamination showed a hard-inelastic swelling in epi-mesogastric region. Laboratory data showed an increase of leukocytesand elevated level of CA 19-9. Esophagogastroduodenoscopy showed a duodenal vegetans neoformation, subjected toexamination biopsy and bacterial culture. Computed tomography scans showed a voluminous duodenal mass without safeplans of cleavage with the head of the pancreas. The biopsy results were not decisive for the presence of necrotic tissue. Themicrobiological culture was positive for Candida Glabrata mimicking an advanced mycotic abscess. Laparotomy revealed apalpable hard mass in duodenum. Cephalic duodenopancreatectomy was performed.Results: Postoperative period was regular. The patient resume eating during the sixth postoperative day and was discharged ingood conditions. The final histological diagnosis was papillary moderately differentiated adenocarcinoma with expansivegrowth in duodenal wall. There was no lymph node involvement or distant organ metastasis.Conclusions: The duodenal tumors are rare pathologies. There is association with familial adenomatous polyposis, Cronhdisease, alcohol abuse, smoking, peptic ulcer. Diagnosis is based on endoscopic and imaging techniques. The mainprognostic factors are tumor stage, lymph node involvement and metastasis. When is possible we perform a radical approachreserving palliative treatment for advanced neoplasm.

UR - http://hdl.handle.net/10447/82603

M3 - Other

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EP - 37

ER -