Does Conservative Surgery for Breast Carcinoma Still Require Axillary Lymph Node Evaluation? A Retrospective Analysis of 1156 Consecutive Women With Early Breast Cancer

Salvatore Buscemi, Giuseppe Damiano, Antonio Marrazzo, Attilio Ignazio Lo Monte, Emilia Marrazzo, Pietra Taormina, Antonio Marrazzo, Emilia Marrazzo

Research output: Contribution to journalArticle

Abstract

The role of axillary surgery for early breast carcinoma treated with conservative surgery and radiotherapy is currently the subject of considerable investigation. Recent studies have supported the noninferiority of avoiding axillary surgery in terms of overall survival when sentinel lymph node biopsy (SLNB) presents ≤ 2 positive lymph nodes, thus sparing the patients from complications. There are some ongoing studies investigating the possibility of omitting SLNB. Axillary study seems to be sufficiently replaced by SLNB for staging the disease. Axillary surgery maintains a therapeutic role in the presence of > 2 metastatic lymph nodes at SLNB.
Original languageEnglish
Pages (from-to)e53-e57
Number of pages5
JournalClinical Breast Cancer
Volume17
Publication statusPublished - 2016

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Sentinel Lymph Node Biopsy
Lymph Nodes
Breast Neoplasms
Radiotherapy
Survival
Therapeutics

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

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title = "Does Conservative Surgery for Breast Carcinoma Still Require Axillary Lymph Node Evaluation? A Retrospective Analysis of 1156 Consecutive Women With Early Breast Cancer",
abstract = "The role of axillary surgery for early breast carcinoma treated with conservative surgery and radiotherapy is currently the subject of considerable investigation. Recent studies have supported the noninferiority of avoiding axillary surgery in terms of overall survival when sentinel lymph node biopsy (SLNB) presents ≤ 2 positive lymph nodes, thus sparing the patients from complications. There are some ongoing studies investigating the possibility of omitting SLNB. Axillary study seems to be sufficiently replaced by SLNB for staging the disease. Axillary surgery maintains a therapeutic role in the presence of > 2 metastatic lymph nodes at SLNB.",
author = "Salvatore Buscemi and Giuseppe Damiano and Antonio Marrazzo and {Lo Monte}, {Attilio Ignazio} and Emilia Marrazzo and Pietra Taormina and Antonio Marrazzo and Emilia Marrazzo",
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AU - Buscemi, Salvatore

AU - Damiano, Giuseppe

AU - Marrazzo, Antonio

AU - Lo Monte, Attilio Ignazio

AU - Marrazzo, Emilia

AU - Taormina, Pietra

AU - Marrazzo, Antonio

AU - Marrazzo, Emilia

PY - 2016

Y1 - 2016

N2 - The role of axillary surgery for early breast carcinoma treated with conservative surgery and radiotherapy is currently the subject of considerable investigation. Recent studies have supported the noninferiority of avoiding axillary surgery in terms of overall survival when sentinel lymph node biopsy (SLNB) presents ≤ 2 positive lymph nodes, thus sparing the patients from complications. There are some ongoing studies investigating the possibility of omitting SLNB. Axillary study seems to be sufficiently replaced by SLNB for staging the disease. Axillary surgery maintains a therapeutic role in the presence of > 2 metastatic lymph nodes at SLNB.

AB - The role of axillary surgery for early breast carcinoma treated with conservative surgery and radiotherapy is currently the subject of considerable investigation. Recent studies have supported the noninferiority of avoiding axillary surgery in terms of overall survival when sentinel lymph node biopsy (SLNB) presents ≤ 2 positive lymph nodes, thus sparing the patients from complications. There are some ongoing studies investigating the possibility of omitting SLNB. Axillary study seems to be sufficiently replaced by SLNB for staging the disease. Axillary surgery maintains a therapeutic role in the presence of > 2 metastatic lymph nodes at SLNB.

UR - http://hdl.handle.net/10447/214286

M3 - Article

VL - 17

SP - e53-e57

JO - Clinical Breast Cancer

JF - Clinical Breast Cancer

SN - 1526-8209

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