The DNA-binding of two salphen-like metal complexes of nickel(II) (1) and zinc(II) (2) was investigated in different ionic strength solutions by absorption spectroscopy. The data analysis allowed us to obtain the values of their extrapolated DNA-binding constant in physiological conditions, with DNA-binding strength in the order Ni > Zn, and to give relative weight to the electrostatic and non-electrostatic contributions to their DNA-interaction.
|Number of pages||3|
|Journal||Journal of Inorganic Biochemistry|
|Publication status||Published - 2020|
All Science Journal Classification (ASJC) codes
- Inorganic Chemistry