Diagnostic techniques and multidisciplinary approach in idiopathic granulomatous mastitis: A revision of the literature

Giuseppe Buscemi, Vincenzo Davide Palumbo, Giuseppe Damiano, Attilio Ignazio Lo Monte, Salvatore Buscemi, Eliana Gulotta, Salvatore Fazzotta, Vincenzo D. Palumbo, Carolina Maione, Gabriele Spinelli

Research output: Contribution to journalArticle

Abstract

Idiopathic granulomatous mastitis (IGM) is a chronic benign inflammatory disease of the breast that may mimic breast cancer. It is most common in parous young fertile women, although it can occur in nulliparous women and in men. IGM is an idiopathic disease due to the influence of some environmental factors in genetically predisposed subjects. Several pathogenic hypothesis have been proposed in the last years (autoimmune, hormonal, infective genesis). IGM presents as a painful palpable mass located in one of the two udders. The skin is usually normal but could present signs of inflammation with or without lymph nodes involvement. Ultrasonography, mammography, magnetic resonance can be diagnosed an IGM, but pathog-nomonic radiological signs has not yet reported in literature. Biopsy findings show granulomatous lesion centered on the breast lobule, as in granulomatous mastitis induced by tuberculosis or sarcoidosis. The aim of this review of literature is to verify the development of new advanced diagnostic techniques and multidisciplinary approach for this condition. In the last years innovative approaches have modified IGM diagnosis and therapy, avoiding surgery in most of cases, introducing a more conservative medical approach based on recent etiopathological hypothesis. (www.actabiomedica.it).
Original languageEnglish
Pages (from-to)11-15
Number of pages5
JournalACTA BIO-MEDICA DE L'ATENEO PARMENSE
Volume90
Publication statusPublished - 2019

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Granulomatous Mastitis
Animal Mammary Glands
Breast Diseases
Mammography
Sarcoidosis
Ultrasonography
Tuberculosis
Breast
Magnetic Resonance Spectroscopy
Lymph Nodes
Breast Neoplasms
Inflammation
Biopsy
Skin

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "Diagnostic techniques and multidisciplinary approach in idiopathic granulomatous mastitis: A revision of the literature",
abstract = "Idiopathic granulomatous mastitis (IGM) is a chronic benign inflammatory disease of the breast that may mimic breast cancer. It is most common in parous young fertile women, although it can occur in nulliparous women and in men. IGM is an idiopathic disease due to the influence of some environmental factors in genetically predisposed subjects. Several pathogenic hypothesis have been proposed in the last years (autoimmune, hormonal, infective genesis). IGM presents as a painful palpable mass located in one of the two udders. The skin is usually normal but could present signs of inflammation with or without lymph nodes involvement. Ultrasonography, mammography, magnetic resonance can be diagnosed an IGM, but pathog-nomonic radiological signs has not yet reported in literature. Biopsy findings show granulomatous lesion centered on the breast lobule, as in granulomatous mastitis induced by tuberculosis or sarcoidosis. The aim of this review of literature is to verify the development of new advanced diagnostic techniques and multidisciplinary approach for this condition. In the last years innovative approaches have modified IGM diagnosis and therapy, avoiding surgery in most of cases, introducing a more conservative medical approach based on recent etiopathological hypothesis. (www.actabiomedica.it).",
author = "Giuseppe Buscemi and Palumbo, {Vincenzo Davide} and Giuseppe Damiano and {Lo Monte}, {Attilio Ignazio} and Salvatore Buscemi and Eliana Gulotta and Salvatore Fazzotta and Palumbo, {Vincenzo D.} and Carolina Maione and Gabriele Spinelli",
year = "2019",
language = "English",
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pages = "11--15",
journal = "Acta Biomedica de l'Ateneo Parmense",
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T1 - Diagnostic techniques and multidisciplinary approach in idiopathic granulomatous mastitis: A revision of the literature

AU - Buscemi, Giuseppe

AU - Palumbo, Vincenzo Davide

AU - Damiano, Giuseppe

AU - Lo Monte, Attilio Ignazio

AU - Buscemi, Salvatore

AU - Gulotta, Eliana

AU - Fazzotta, Salvatore

AU - Palumbo, Vincenzo D.

AU - Maione, Carolina

AU - Spinelli, Gabriele

PY - 2019

Y1 - 2019

N2 - Idiopathic granulomatous mastitis (IGM) is a chronic benign inflammatory disease of the breast that may mimic breast cancer. It is most common in parous young fertile women, although it can occur in nulliparous women and in men. IGM is an idiopathic disease due to the influence of some environmental factors in genetically predisposed subjects. Several pathogenic hypothesis have been proposed in the last years (autoimmune, hormonal, infective genesis). IGM presents as a painful palpable mass located in one of the two udders. The skin is usually normal but could present signs of inflammation with or without lymph nodes involvement. Ultrasonography, mammography, magnetic resonance can be diagnosed an IGM, but pathog-nomonic radiological signs has not yet reported in literature. Biopsy findings show granulomatous lesion centered on the breast lobule, as in granulomatous mastitis induced by tuberculosis or sarcoidosis. The aim of this review of literature is to verify the development of new advanced diagnostic techniques and multidisciplinary approach for this condition. In the last years innovative approaches have modified IGM diagnosis and therapy, avoiding surgery in most of cases, introducing a more conservative medical approach based on recent etiopathological hypothesis. (www.actabiomedica.it).

AB - Idiopathic granulomatous mastitis (IGM) is a chronic benign inflammatory disease of the breast that may mimic breast cancer. It is most common in parous young fertile women, although it can occur in nulliparous women and in men. IGM is an idiopathic disease due to the influence of some environmental factors in genetically predisposed subjects. Several pathogenic hypothesis have been proposed in the last years (autoimmune, hormonal, infective genesis). IGM presents as a painful palpable mass located in one of the two udders. The skin is usually normal but could present signs of inflammation with or without lymph nodes involvement. Ultrasonography, mammography, magnetic resonance can be diagnosed an IGM, but pathog-nomonic radiological signs has not yet reported in literature. Biopsy findings show granulomatous lesion centered on the breast lobule, as in granulomatous mastitis induced by tuberculosis or sarcoidosis. The aim of this review of literature is to verify the development of new advanced diagnostic techniques and multidisciplinary approach for this condition. In the last years innovative approaches have modified IGM diagnosis and therapy, avoiding surgery in most of cases, introducing a more conservative medical approach based on recent etiopathological hypothesis. (www.actabiomedica.it).

UR - http://hdl.handle.net/10447/368124

M3 - Article

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SP - 11

EP - 15

JO - Acta Biomedica de l'Ateneo Parmense

JF - Acta Biomedica de l'Ateneo Parmense

SN - 0392-4203

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