Diagnostic accuracy of 64-slice CT in the assessment of coronary stents.

Ludovico La Grutta, Massimo Midiri, Willem B. Meijboom, Palumbo, Ludovico La Grutta, Erica Maffei, Vignali, Alberto Menozzi, Reverberi, Nico R. Mollet, Ardissino, Filippo Cademartiri, Gabriel P. Krestin, Pugliese, Giuseppe Runza

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Abstract

PURPOSE: The purpose of this study was to assess the diagnostic accuracy of 64-slice computed tomography (64-CT) coronary angiography in the detection of coronary in-stent restenosis. MATERIALS AND METHODS: Ninety-five patients (72 men and 23 women, mean age 58+/-8 years) with previous percutaneous coronary intervention with stenting and suspected restenosis underwent 64-CT (Sensation 64, Siemens). The mean time between stent deployment and 64-CT was 6.1+/-4.2 months. The scan parameters were: slices 32 x 2, individual detector width 0.6 mm, rotation time 0.33 s, feed 3.84 mm/rotation, 120 kV, 900 mAs. After the intravenous administration of iodinated contrast material (Iomeprol 400 mgI/ml, Iomeron, Bracco) and a bolus chaser (40 ml of saline), the scan was completed in <12 s. All coronary segments with a stent were assessed on 64-CT by two observers in consensus and judged as: patent, with intimal hyperplasia (lumen reduction of <50%), with in-stent restenosis (> or =50%), or with in-stent occlusion (100%). The consensus reading was compared with conventional coronary angiography. RESULTS: Four patients were excluded because of insufficient image quality. In the remaining 91, we assessed 102 stents (31 RCA; 10 LM; 54 LAD; 7 CX). In 14 (13.7%) stents, in-stent restenosis (n=8) or in-stent occlusion (n=6) was found. Intimal hyperplasia was detected in 11 (10.8%) stents. The sensitivity and negative predictive value of 64-CT for in-stent occlusion were 100% and 100%, respectively, whereas for all stenoses, >50% they were 92.9% and 98.7%, respectively. CONCLUSIONS: We found that 64-CT has a high diagnostic accuracy for the detection of in-stent restenosis in a selected patient population.
Original languageEnglish
Number of pages0
JournalLA RADIOLOGIA MEDICA
Volume2007-06
Publication statusPublished - 2007

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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    La Grutta, L., Midiri, M., Meijboom, W. B., Palumbo, La Grutta, L., Maffei, E., Vignali, Menozzi, A., Reverberi, Mollet, N. R., Ardissino, Cademartiri, F., Krestin, G. P., Pugliese, & Runza, G. (2007). Diagnostic accuracy of 64-slice CT in the assessment of coronary stents. LA RADIOLOGIA MEDICA, 2007-06.