Development and characterization of xyloglucan-poly(vinyl alcohol) hydrogel membrane for Wireless Smart wound dressings

Alessia Ajovalasit, Clelia Dispenza, Massimiliano Zingales, Cecilia Occhiuzzi, Gioacchino Alotta, Maria Antonietta Sabatino, Cecilia Occhiuzzi, Clelia Dispenza, Sara Amendola, Maria Cristina Caccami, Daniela Giacomazza, Gaetano Marrocco

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Hydrogel-based smart wound dressings that combine the traditional favourable properties of hydrogels as skin care materials with sensing functions of relevant biological parameters for the remote monitoring of wound healing are under development. In particular, lightweight, ultra-high frequency radiofrequency identification (UHF RFID) sensor are adjoined to xyloglucan-poly(vinyl alcohol) hydrogel films to battery-less monitor moisture level of the bandage in contact with the skin, as well as wireless transmit the measured data to an off-body reader. This study investigates the swelling behavior of the hydrogels in contact with simulated biological fluids, and the modification of their morphology, mechanical properties, and dielectric properties in a wide range of frequencies (100–106Hz and 108–1011Hz). The films absorb simulated body fluids up to approximately four times their initial weight, without losing their integrity but undergoing significant microstructural changes. We observed relevant linear increases of electric conductivity and permittivity with the swelling degree, with an abrupt change of slope that is related to the network rearrangements occurring upon swelling.
Original languageEnglish
Pages (from-to)214-222
Number of pages9
JournalEuropean Polymer Journal
Publication statusPublished - 2018

All Science Journal Classification (ASJC) codes

  • Materials Chemistry
  • Physics and Astronomy(all)
  • Polymers and Plastics
  • Organic Chemistry

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