Dental pulp stem cells for bone tissue engineering: a review of the current literature and a look to the future

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15 Citations (Scopus)

Abstract

The aim of this narrative review is to investigate the implication of mesenchymal stem cells harvested fromhuman dental pulp in in vivo bone tissue regeneration. We focused on studies related to roles of humandental pulp stem cells in in vivo bone regeneration. A total of 1021 studies were identified; after theassessment of eligibility, only 39 studies were included in the review. The evaluated information of thestudies regards the experimental strategies (e.g., the isolation method, the scaffold, the in vivo animalmodels). The overall main evidences highlighted from the analysis are that dental pulp stem cells andhuman-exfoliated deciduous teeth stem cells supported by a suitable scaffold should be considered avaluable source for bone tissue regeneration.
Original languageEnglish
Pages (from-to)207-218
Number of pages12
JournalRegenerative Medicine
Volume13
Publication statusPublished - 2018

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Embryology

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