CT and MR imaging of chemotherapy-induced hepatopathy

Federica Vernuccio, Giuseppe Brancatelli, Giuseppe Badalamenti, Massimo Midiri, Federica Vernuccio, Marco Dioguardi Burgio, Silvestro Cusmà, Filippo Barbiera, Valérie Vilgrain, Marco Dioguardi Burgio

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Chemotherapy-induced hepatopathy includes a wide variety of parenchymal and vascular hepatic changes on imaging, including diffuse or focal hepatopathies (i.e. hepatitis, steatosis, fibrosis, pseudocirrhosis, or sinusoidal obstruction). These changes can profoundly alter the hepatic parenchyma on imaging and result in both false negative and false-positive diagnoses of hepatic metastases and lead to errors in patient management strategies. It is therefore important for radiologists to have a comprehensive knowledge of the imaging patterns that may develop following chemotherapy. The purpose of this review is to explore the broad spectrum of hepatic parenchymal and vascular chemotherapy-induced changes on CT and MR imaging.
Original languageEnglish
Pages (from-to)3312-3324
Number of pages13
JournalAbdominal Radiology
Publication statusPublished - 2019

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

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