Collateral non cardiac findings in clinical routine CT coronary angiography: results from a multi-center registry

Ludovico La Grutta, Massimo Midiri, Roberto Lagalla, Alberto Clemente, Erica Maffei, Chiara Martini, Teresa Arcadi, Andrea Pezzato, Alessandra Zuccarelli, Camilla Barbiani, Nico R. Mollet, Filippo Cademartiri, Roberto Pozzi Mucelli, Gabriel P. Krestin, Roberto Malagò

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Abstract

Purpose: The aim of the study was to evaluate the prevalence of collateral findings detected in computed tomography coronary angiography (CTCA) in a multi-center registry. Materials and methods: We performed a retrospective review of 4303 patients (2719 males, mean age 60.3 ± 10.2 years) undergoing 64-slice CTCA for suspected or known coronary artery disease (CAD) at various academic institutions between 01/2006 and 09/2010. Collateral findings were recorded and scored as: non-significant (no signs of relevant pathology, not necessary to be reported), significant (clear signs of pathology, mandatory to be reported), or major (remarkable pathology, mandatory to be reported and further investigated). Results: We detected 6886 non-cardiac findings (1.6 non cardiac finding per patient). Considering all centers, only 865/4303 (20.1 %) patients were completely without any additional finding. Overall, 2095 (30.4 %) non-significant, 4486 (65.2 %) significant, and 305 (4.4 %) major findings were detected. Among major findings, primary lung cancer was reported in 21 cases. In every center, most prevalent significant findings were mediastinal lymph nodes >1 cm. In 256 patients, collateral findings were clinically more relevant than coexisting CAD and justified the symptoms of patients. Conclusions: The prevalence of significant and major collateral findings in CTCA is high. Radiologists should carefully evaluate the entire scan volume in each patient.
Original languageEnglish
Pages (from-to)1122-1129
Number of pages8
JournalLA RADIOLOGIA MEDICA
Volume120
Publication statusPublished - 2015

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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    La Grutta, L., Midiri, M., Lagalla, R., Clemente, A., Maffei, E., Martini, C., Arcadi, T., Pezzato, A., Zuccarelli, A., Barbiani, C., Mollet, N. R., Cademartiri, F., Pozzi Mucelli, R., Krestin, G. P., & Malagò, R. (2015). Collateral non cardiac findings in clinical routine CT coronary angiography: results from a multi-center registry. LA RADIOLOGIA MEDICA, 120, 1122-1129.