TY - JOUR
T1 - CLONING OF RAT-SPECIFIC LONG PCP4/PEP19 ISOFORM (LPI)
AU - Di Liegro, Italia
AU - Schiera, Gabriella
AU - Proia, Patrizia
AU - Aflalo-Rattenbach, Revital
AU - Créau, Nicole
PY - 2007
Y1 - 2007
N2 - We report the identification of a cDNA that encodes a putative protein of 94 amino acids and expected molecular weight of 10.7 kDa, the C-terminal half of which is identical to that of PEP19, a small, brain-specific protein involved in Ca++/calmodulin signaling. The novel rat-specific protein, tentatively named long PEP19 isoform (LPI), is the product of alternative splicing of the rat PCP4 gene encoding PEP19. We found that antibodies raised against the first 13 N-terminal amino acids of LPI, not present in PEP19, recognize a protein enriched in the developing rat brain.
AB - We report the identification of a cDNA that encodes a putative protein of 94 amino acids and expected molecular weight of 10.7 kDa, the C-terminal half of which is identical to that of PEP19, a small, brain-specific protein involved in Ca++/calmodulin signaling. The novel rat-specific protein, tentatively named long PEP19 isoform (LPI), is the product of alternative splicing of the rat PCP4 gene encoding PEP19. We found that antibodies raised against the first 13 N-terminal amino acids of LPI, not present in PEP19, recognize a protein enriched in the developing rat brain.
KW - Ca++/calmodulin signaling
KW - LPI
KW - rat brain
KW - Ca++/calmodulin signaling
KW - LPI
KW - rat brain
UR - http://hdl.handle.net/10447/36893
M3 - Article
VL - 2007
SP - 501
EP - 509
JO - International Journal of Molecular Medicine
JF - International Journal of Molecular Medicine
SN - 1107-3756
ER -