CLONING OF RAT-SPECIFIC LONG PCP4/PEP19 ISOFORM (LPI)

Patrizia Proia, Italia Di Liegro, Gabriella Schiera, Revital Aflalo-Rattenbach, Nicole Créau

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

We report the identification of a cDNA that encodes a putative protein of 94 amino acids and expected molecular weight of 10.7 kDa, the C-terminal half of which is identical to that of PEP19, a small, brain-specific protein involved in Ca++/calmodulin signaling. The novel rat-specific protein, tentatively named long PEP19 isoform (LPI), is the product of alternative splicing of the rat PCP4 gene encoding PEP19. We found that antibodies raised against the first 13 N-terminal amino acids of LPI, not present in PEP19, recognize a protein enriched in the developing rat brain.
Original languageEnglish
Pages (from-to)501-509
Number of pages9
JournalInternational Journal of Molecular Medicine
Volume2007
Publication statusPublished - 2007

All Science Journal Classification (ASJC) codes

  • Genetics

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