Chirurgia trans-cranica mediante ultrasuoni focalizzati ad alta intensità su guida rm: esperienza preliminare a 1,5T (primi 2 casi trattati)

Cesare Gagliardo, Massimo Midiri, Domenico Iacopino, Antonella Giugno, Laura Geraci

Research output: Contribution to conferenceOtherpeer-review

Abstract

[automatically translated] Scope of Work We present the preliminary results obtained with the first Italian installation of equipment for functional neurosurgery using high intensity focused ultrasound to MRI guidance (trans-cranial MRI-guided Focused Ultrasound Surgery, tcMRgFUS); This is among other things the first tcMRgFUS equipment to the world ever installed on a 1.5T MRI scanner. This equipment is currently certified (CE and FDA) for functional neurosurgery treatment in patients with essential tremor (Essential Tremor, ET), idiopathic Parkinson (Parkinson's Disease, PD) unilateral mainly tremorigeno and neuropathic pain (Neuropathic Pain, NP). Materials and Methods: We enrolled patients with neurological disorders resistant to medical indication and treatment of functional neurosurgery treatment. Before treatment was harvesting a detailed medical history and each patient underwent a clinical neurological examination and complete neurophysiological. Eligible patients underwent CT and MRI screening to rule out contraindications to treatment. The tcMRgFUS treatments were carried out by a multidisciplinary team led by a neurosurgeon with proven experience in functional neurosurgery and a neuroradiologist, optimizing treatment parameters case by case. Results Although this is a preliminary experience, the success of the first treatments from us effected, laid the ground for future, innovative functional neurosurgical treatment using tcMRgFUS (currently performed in a few centers in the world using only 3T MR scanner ), They can also be performed effectively with the most popular operating at 1.5T MR scanner. In the treatments up to now executed complications were recorded no intra- or post-treatment. Treated patients almost immediately achieved a clinical benefit and were discharged after 48 hours of treatment. Conclusion Being able to perform interventions for functional neurosurgery with a non-invasive technique that does not use ionizing radiation, which allows you to verify the clinical efficacy of treatment before they lead to permanent brain injury and all this using the most common MRI scanner operating at 1.5T is a huge step forward for both the interventional radiology for functional neurosurgery. In the treatments up to now executed complications were recorded no intra- or post-treatment. Treated patients almost immediately achieved a clinical benefit and were discharged after 48 hours of treatment. Conclusion Being able to perform interventions for functional neurosurgery with a non-invasive technique that does not use ionizing radiation, which allows you to verify the clinical efficacy of treatment before they lead to permanent brain injury and all this using the most common MRI scanner operating at 1.5T is a huge step forward for both the interventional radiology for functional neurosurgery. In the treatments up to now executed complications were recorded no intra- or post-treatment. Treated patients almost immediately achieved a clinical benefit and were discharged after 48 hours of treatment. Conclusion Being able to perform interventions for functional neurosurgery with a non-invasive technique that does not use ionizing radiation, which allows you to verify the clinical efficacy of treatment before they lead to permanent brain injury and all this using the most common MRI scanner operating at 1.5T is a huge step forward for both the interventional radiology for functional neurosurgery. Treated patients almost immediately achieved a clinical benefit and were discharged after 48 hours of treatment. Conclusion Being ab
Original languageItalian
Number of pages1
Publication statusPublished - 2015

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