Characterization of phenolic pellets for ESR dosimetry in photon beam radiotherapy

Anna Longo, Antonio Bartolotta, Salvatore Gallo, Maurizio Marrale, Eleonora Mones, Gianfranco Loi, Maurizio Marrale, Salvatore Panzeca, Salvatore Gallo, Giuseppina Iacoviello, Anna Maria Gueli, Ivan Veronese, Daniele Dondi, Salvatore Panzeca

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This work deals with the dosimetric features of a particular phenolic compound (IRGANOX 1076 ® ) for dosimetry of clinical photon beams by using electron spin resonance (ESR) spectroscopy. After the optimization of the ESR readout parameters (namely modulation amplitude and microwave power) to maximise the signal without excessive spectrum distortions, basic dosimetric properties of laboratory-made phenolic dosimeters in pellet form, such as reproducibility, dose–response, sensitivity, linearity and dose rate dependence were investigated. The dosimeters were tested by measuring the depth dose profile of a 6 MV photon beam. A satisfactory intra-batch reproducibility of the ESR signal of the manufactured dosimeters was obtained. The ESR signal proved to increase linearly with increasing dose in the investigated dose range 1–13 Gy. The presence of an intrinsic background signal limits the minimum detectable dose to a value of approximately 0.6 Gy. Reliable and accurate assessment of the dose was achieved, independently of the dose rate. Such characteristics, together with the fact that IRGANOX 1076 ® is almost tissue-equivalent, and the stability of the ESR signal, make these dosimeters promising materials for ESR dosimetric applications in radiotherapy.
Original languageEnglish
Pages (from-to)471-480
Number of pages10
JournalRadiation and Environmental Biophysics
Volume56
Publication statusPublished - 2017

Fingerprint

photon beams
Electron Spin Resonance Spectroscopy
electron spin resonance
Photons
pellets
dosimeters
radiation therapy
electron paramagnetic resonance
Radiotherapy
dosage
Microwaves
phenolic compound
linearity
dose
readout
spectroscopy
Radiation Dosimeters
microwaves
optimization
sensitivity

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Radiation
  • Environmental Science(all)

Cite this

Characterization of phenolic pellets for ESR dosimetry in photon beam radiotherapy. / Longo, Anna; Bartolotta, Antonio; Gallo, Salvatore; Marrale, Maurizio; Mones, Eleonora; Loi, Gianfranco; Marrale, Maurizio; Panzeca, Salvatore; Gallo, Salvatore; Iacoviello, Giuseppina; Gueli, Anna Maria; Veronese, Ivan; Dondi, Daniele; Panzeca, Salvatore.

In: Radiation and Environmental Biophysics, Vol. 56, 2017, p. 471-480.

Research output: Contribution to journalArticle

Longo, A, Bartolotta, A, Gallo, S, Marrale, M, Mones, E, Loi, G, Marrale, M, Panzeca, S, Gallo, S, Iacoviello, G, Gueli, AM, Veronese, I, Dondi, D & Panzeca, S 2017, 'Characterization of phenolic pellets for ESR dosimetry in photon beam radiotherapy', Radiation and Environmental Biophysics, vol. 56, pp. 471-480.
Longo, Anna ; Bartolotta, Antonio ; Gallo, Salvatore ; Marrale, Maurizio ; Mones, Eleonora ; Loi, Gianfranco ; Marrale, Maurizio ; Panzeca, Salvatore ; Gallo, Salvatore ; Iacoviello, Giuseppina ; Gueli, Anna Maria ; Veronese, Ivan ; Dondi, Daniele ; Panzeca, Salvatore. / Characterization of phenolic pellets for ESR dosimetry in photon beam radiotherapy. In: Radiation and Environmental Biophysics. 2017 ; Vol. 56. pp. 471-480.
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AU - Loi, Gianfranco

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