Characterization of Bacillus thuringiensis isolated from infections in burn wounds

Maria Valeria Torregrossa, Per H. Damgaard, José Bresciani, Jørgen Eilenberg, Per E. Granum

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Four strains of Bacillus thuringiensis were isolated from infections in burn wounds and from water used in the treatment of burn wounds. The strains produced large parasporal inclusion bodies composed of 141, 83, and 81 kDa protoxins. The four strains were tested for insecticidal activity against larvae of Pieris brassicae and Aedes aegypti but showed no activity; Vero cell assays for the production of enterotoxins were also negative. Attempts to classify the strains according to flagellar H-serotype showed them all to be non-flagellated. Apart from two occupational health accidents that occurred during the handling of highly concentrated B. thuringiensis fluids, this is the first report of B. thuringiensis causing non-gastrointestinal clinical infection in immunosuppressed patients.
Original languageEnglish
Pages (from-to)47-53
Number of pages7
JournalFEMS Immunology and Medical Microbiology
Volume18
Publication statusPublished - 1997

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Microbiology (medical)
  • Infectious Diseases

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