Cerebral abscesses imaging: A practical approach

Cesare Gagliardo, Paola Feraco, Davide Donner, Luc Van Den Hauwe, Benedetto Petralia, Silvia Piccinini, Anna Del Poggio, Irene Leonardi, Anna Del Poggio, Rossana Franciosi, Benedetto Petralia

Research output: Contribution to journalArticlepeer-review


Brain abscesses (BAs) are focal infections of the central nervous system (CNS) that start as a localised area of weakening of the brain parenchyma (cerebritis) and develops into a collection of pus surrounded by a capsule. Pyogenic (bacterial) BAs represent the majority of all BAs; in some cases, the diagnostic and therapeutic management can be challenging. Imaging has a primary role in differentiating BAs from other lesions. Conventional magnetic resonance imaging (cMRI) is essential for the identification of the lesion, its localisation and its morphological features. However, cMRI does not allow to reliably differentiate BAs from other intracranial mass lesions such as necrotic tumours. Advanced sequences, such as diffu-sion-weighted imaging (DWI), perfusion-weighted imaging (PWI) and proton MR spectroscopy (1H-MRS) are very useful in the differential diagnosis from other brain lesions, such as non-pyogenic abscesses or necrotic tumours, and provide essential information on structural, vascular and meta-bolic characteristics allowing greater neuroradiological confidence. The aim of this pictorial review is to provide a practical approach showing the added value of more advanced MRI techniques in their diagnostic management.
Original languageEnglish
Pages (from-to)e14-e27
Number of pages14
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Health Policy
  • Pharmacology (medical)


Dive into the research topics of 'Cerebral abscesses imaging: A practical approach'. Together they form a unique fingerprint.

Cite this