Caecal leiomyoma detected by whole-body MRI in a patient with hodgkin lymphoma: First case report

Roberto Lagalla, Domenico Albano, Emanuele Sinagra, Massimo Galia, Massimo Midiri, Giuseppe Di Buono, Antonino Agrusa, Dario Raimondo, Emanuele Sinagra, Caterina Patti, Donatella Narese

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2 Citations (Scopus)

Abstract

Introduction. Hodgkin Lymphoma (HL) is one of the most curable malignant diseases. Modern treatments, like the combined radiochemotherapy and stem cell transplantation, have increased the number of malignant disease survivors. However, HL survivors are at risk of long-term effects, including the development of solid tumors. Secondary neoplasms are a major cause of late morbidity and mortality following treatment for HL. Case report. We report the case of a male patient, treated for HL by chemotherapy, who developed a large leiomyoma of the cecum one year after the treatment. A whole-body Magnetic Resonance (WBMRI) scan performed during the follow-up allowed the detection of this incidental caecal mass that was absent in a Computed Tomography (CT) scan performed immediately after the treatment. After a CT-guided biopsy, the lesion was surgically removed and the diagnosis of caecal leiomyoma was obtained. Discussion. To our knowledge, this is the first case report, according to the scientific literature, of caecal leiomyoma developing after chemotherapy in a HL survivor. Leiomyoma is a rare benign tumor that usually appears as a solitary small mass with a nodular growth and a benign course. Conclusion. This case shows that WB-MRI allows detecting relevant incidental findings during the oncologic follow-up, avoiding both radiation exposure and contrast agent administration. Furthermore, leiomyoma should be considered in the differential diagnosis between the caecal masses with high growth rate.
Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalIL GIORNALE DI CHIRURGIA
Volume38
Publication statusPublished - 2017

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Leiomyoma
Hodgkin Disease
Survivors
Tomography
Literature
Drug Therapy
Neoplasms
Incidental Findings
Cecum
Stem Cell Transplantation
Chemoradiotherapy
Therapeutics
Growth
Contrast Media
Differential Diagnosis
Magnetic Resonance Spectroscopy
Morbidity
Biopsy
Mortality

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

@article{7944e36dbbde4b1aa33cef061a0ff084,
title = "Caecal leiomyoma detected by whole-body MRI in a patient with hodgkin lymphoma: First case report",
abstract = "Introduction. Hodgkin Lymphoma (HL) is one of the most curable malignant diseases. Modern treatments, like the combined radiochemotherapy and stem cell transplantation, have increased the number of malignant disease survivors. However, HL survivors are at risk of long-term effects, including the development of solid tumors. Secondary neoplasms are a major cause of late morbidity and mortality following treatment for HL. Case report. We report the case of a male patient, treated for HL by chemotherapy, who developed a large leiomyoma of the cecum one year after the treatment. A whole-body Magnetic Resonance (WBMRI) scan performed during the follow-up allowed the detection of this incidental caecal mass that was absent in a Computed Tomography (CT) scan performed immediately after the treatment. After a CT-guided biopsy, the lesion was surgically removed and the diagnosis of caecal leiomyoma was obtained. Discussion. To our knowledge, this is the first case report, according to the scientific literature, of caecal leiomyoma developing after chemotherapy in a HL survivor. Leiomyoma is a rare benign tumor that usually appears as a solitary small mass with a nodular growth and a benign course. Conclusion. This case shows that WB-MRI allows detecting relevant incidental findings during the oncologic follow-up, avoiding both radiation exposure and contrast agent administration. Furthermore, leiomyoma should be considered in the differential diagnosis between the caecal masses with high growth rate.",
author = "Roberto Lagalla and Domenico Albano and Emanuele Sinagra and Massimo Galia and Massimo Midiri and {Di Buono}, Giuseppe and Antonino Agrusa and Dario Raimondo and Emanuele Sinagra and Caterina Patti and Donatella Narese",
year = "2017",
language = "English",
volume = "38",
pages = "27--32",
journal = "Giornale di Chirurgia",
issn = "0391-9005",
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}

TY - JOUR

T1 - Caecal leiomyoma detected by whole-body MRI in a patient with hodgkin lymphoma: First case report

AU - Lagalla, Roberto

AU - Albano, Domenico

AU - Sinagra, Emanuele

AU - Galia, Massimo

AU - Midiri, Massimo

AU - Di Buono, Giuseppe

AU - Agrusa, Antonino

AU - Raimondo, Dario

AU - Sinagra, Emanuele

AU - Patti, Caterina

AU - Narese, Donatella

PY - 2017

Y1 - 2017

N2 - Introduction. Hodgkin Lymphoma (HL) is one of the most curable malignant diseases. Modern treatments, like the combined radiochemotherapy and stem cell transplantation, have increased the number of malignant disease survivors. However, HL survivors are at risk of long-term effects, including the development of solid tumors. Secondary neoplasms are a major cause of late morbidity and mortality following treatment for HL. Case report. We report the case of a male patient, treated for HL by chemotherapy, who developed a large leiomyoma of the cecum one year after the treatment. A whole-body Magnetic Resonance (WBMRI) scan performed during the follow-up allowed the detection of this incidental caecal mass that was absent in a Computed Tomography (CT) scan performed immediately after the treatment. After a CT-guided biopsy, the lesion was surgically removed and the diagnosis of caecal leiomyoma was obtained. Discussion. To our knowledge, this is the first case report, according to the scientific literature, of caecal leiomyoma developing after chemotherapy in a HL survivor. Leiomyoma is a rare benign tumor that usually appears as a solitary small mass with a nodular growth and a benign course. Conclusion. This case shows that WB-MRI allows detecting relevant incidental findings during the oncologic follow-up, avoiding both radiation exposure and contrast agent administration. Furthermore, leiomyoma should be considered in the differential diagnosis between the caecal masses with high growth rate.

AB - Introduction. Hodgkin Lymphoma (HL) is one of the most curable malignant diseases. Modern treatments, like the combined radiochemotherapy and stem cell transplantation, have increased the number of malignant disease survivors. However, HL survivors are at risk of long-term effects, including the development of solid tumors. Secondary neoplasms are a major cause of late morbidity and mortality following treatment for HL. Case report. We report the case of a male patient, treated for HL by chemotherapy, who developed a large leiomyoma of the cecum one year after the treatment. A whole-body Magnetic Resonance (WBMRI) scan performed during the follow-up allowed the detection of this incidental caecal mass that was absent in a Computed Tomography (CT) scan performed immediately after the treatment. After a CT-guided biopsy, the lesion was surgically removed and the diagnosis of caecal leiomyoma was obtained. Discussion. To our knowledge, this is the first case report, according to the scientific literature, of caecal leiomyoma developing after chemotherapy in a HL survivor. Leiomyoma is a rare benign tumor that usually appears as a solitary small mass with a nodular growth and a benign course. Conclusion. This case shows that WB-MRI allows detecting relevant incidental findings during the oncologic follow-up, avoiding both radiation exposure and contrast agent administration. Furthermore, leiomyoma should be considered in the differential diagnosis between the caecal masses with high growth rate.

UR - http://hdl.handle.net/10447/239752

UR - http://www.giornalechirurgia.it

M3 - Article

VL - 38

SP - 27

EP - 32

JO - Giornale di Chirurgia

JF - Giornale di Chirurgia

SN - 0391-9005

ER -