Bone Marrow Biopsy in Hodgkin Lymphoma

Ada Maria Florena, Vito Franco, Claudio Tripodo, Aroldo Rizzo, Mario Stella, Vito Franco, Mario Stella

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


In the study of patients with Hodgkin's lymphoma (HL) the evaluation of bone marrow biopsy (BMB) can be difficult. In this review we analyze the main diagnostic features and the clinical risk factors of BM involvement. Although the role of BMB is criticized by some authors, its value is irreplaceable in the staging of HL and in the diagnosis of primary medullary HL. The Ann Arbor staging committee criteria should be revised and updated in the light of the current immunohistochemical studies that give a fundamental help in the diagnostic process. A single BMB should be adequate for diagnosis in most instances. In cases of suspicious involvement a controlateral BMB could be performed.
Original languageEnglish
Pages (from-to)149-155
Number of pages7
JournalEuropean Journal of Haematology
Publication statusPublished - 2004

All Science Journal Classification (ASJC) codes

  • Hematology


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