BILATERAL RENAL ARTERY STENOSIS IN A HYPERTENSIVE LUPUS PATIENT WITHOUT RENAL DYSFUNCTION: A CASE REPORT

Giuseppe Mule', Calogero Geraci, Giulio Geraci, Santina Cottone, Calogero Geraci, Manuela Mogavero, Santina Cottone, Giulio Geraci, Dario Altieri, Benedetto De Biasio, Valentina Cacciatore, Giuseppe Mulè, Dario Altieri, Manuela Mogavero

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3 Citations (Scopus)

Abstract

Systemic lupus erythematosus (SLE) is associated with a high prevalence of atherosclero-sis and an enhanced cardiovascular mortality. In adult subjects, several studies have shown the coexistence of SLE and renal artery stenosis, most of them with unilateral in-volvement or with renal dysfunction.We observed a 62-year-old man with SLE and a 10-year history of moderate-to-severe hy-pertension who was admitted to our hospital because of uncontrolled blood pressure val-ues (152/95 mmHg), despite drug therapy. No signs of renal impairment were evident.After an initial physical examination, which presented a periumbilical bruit, a renal ultra-sound was performed with evidence of bilateral renal artery stenosis. An angio-MR study also confirmed the diagnosis and showed a double renal artery on the right side.Many different factors can contribute to the bilateral renal artery stenosis in this patient. Chronic inflammatory state associated to SLE, metabolic alterations with dyslipidemia and steroid therapy may all be involved in the development of the renal atherosclerotic le-sions.
Original languageEnglish
Pages (from-to)41-44
Number of pages4
JournalEuroMediterranean Biomedical Journal
Volume9
Publication statusPublished - 2014

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Mule', G., Geraci, C., Geraci, G., Cottone, S., Geraci, C., Mogavero, M., Cottone, S., Geraci, G., Altieri, D., De Biasio, B., Cacciatore, V., Mulè, G., Altieri, D., & Mogavero, M. (2014). BILATERAL RENAL ARTERY STENOSIS IN A HYPERTENSIVE LUPUS PATIENT WITHOUT RENAL DYSFUNCTION: A CASE REPORT. EuroMediterranean Biomedical Journal, 9, 41-44.