Anti-inflammatory activity of Citrus bergamia derivatives: Where do we stand?

Elvira Ventura Spagnolo, Nadia Ferlazzo, Michele Navarra, Santa Cirmi, Gioacchino Calapai, Sebastiano Gangemi, Gioacchino Calapai, Michele Navarra, Nadia Ferlazzo, Santa Cirmi

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)


Inflammatory diseases affect a large portion of the worldwide population, and chronic inflammation is a major risk factor for several dangerous pathologies. To limit the side effects of both synthetic and biological anti-inflammatory drugs, the use of herbal medicines, nutraceuticals and food supplements has increased tremendously as alternative and/or complementary medicine to treat several pathologies, including inflammation. During the last decades, the biological properties of Citrus bergamia (bergamot) derivatives have obtained important scientific achievements, and it has been suggested their use in a context of a multitarget pharmacological strategy. Here, we present an overview of the anti-inflammatory properties of bergamot extracts that could represent the scientific basis for develop novel and alternative strategies to improve health status and attenuate inflammatory conditions.
Original languageEnglish
Pages (from-to)1273-
Number of pages11
Publication statusPublished - 2016

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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