Alanine films for EPR dosimetry of low-energy (1–30 keV) X-ray photons

Maria Cristina D'Oca, Giorgio Collura, Leonardo Abbene, Fabio Principato, Maurizio Marrale, Antonio Bartolotta, Marrale, Collura, Bartolotta, D'Oca, Francesco D'Errico, Francesco D'Errico

Research output: Contribution to journalArticle

Abstract

L-alpha-alanine has aroused considerable interest for use in radiation EPR dosimetry and has been formally accepted as a secondary standard for high-dose (kGy) and transfer dosimetry of high-energy photons and electrons. In this work, we extended the investigation of the energy response of alanine EPR films in the low energy range for X-photons (1–30 keV). Electron Paramagnetic Resonance (EPR) measurements were performed on Kodak BioMax alanine films exposed to low-energy X-rays from a Cu-, W- and Mo-targets tube operating at voltages up to 30 kV. Films were chosen because of the low penetration of the soft X-rays used. The response of alanine to low-energy X-rays was characterized experimentally and the relative response (with respect to high energy photons) was found to be between 0.8 and 0.9 for Cu- and W-tube X-rays, and 1.0 for Mo-tube X-rays. The attenuation profiles were investigated and it was found that 1 mm of film material reduces the intensity of the X-ray-beam by about 70%, 50% and 40% for Cu-, W- and Mo-tube X-rays, respectively. Monte Carlo simulations were performed to model the energy release as well as the depth dose profiles for the various radiation beams used. These data are considered relevant for dosimetric applications in low energy beams such the high-gradient treatment fields used in monoenergetic microbeam radiation therapy (MRT) with synchrotron radiation as well as in brachytherapy with low energy sources, for instance 169Yb.
Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalNUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION B, BEAM INTERACTIONS WITH MATERIALS AND ATOMS
Volume459
Publication statusPublished - 2019

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alanine
X ray tubes
Dosimetry
dosimeters
Paramagnetic resonance
electron paramagnetic resonance
Photons
X rays
photons
x rays
tubes
Radiation
energy
Radiotherapy
Synchrotron radiation
dosage
microbeams
Electrons
Electric potential
energy sources

All Science Journal Classification (ASJC) codes

  • Nuclear and High Energy Physics
  • Instrumentation

Cite this

@article{2973caf95dfe40fb905ab80e05218641,
title = "Alanine films for EPR dosimetry of low-energy (1–30 keV) X-ray photons",
abstract = "L-alpha-alanine has aroused considerable interest for use in radiation EPR dosimetry and has been formally accepted as a secondary standard for high-dose (kGy) and transfer dosimetry of high-energy photons and electrons. In this work, we extended the investigation of the energy response of alanine EPR films in the low energy range for X-photons (1–30 keV). Electron Paramagnetic Resonance (EPR) measurements were performed on Kodak BioMax alanine films exposed to low-energy X-rays from a Cu-, W- and Mo-targets tube operating at voltages up to 30 kV. Films were chosen because of the low penetration of the soft X-rays used. The response of alanine to low-energy X-rays was characterized experimentally and the relative response (with respect to high energy photons) was found to be between 0.8 and 0.9 for Cu- and W-tube X-rays, and 1.0 for Mo-tube X-rays. The attenuation profiles were investigated and it was found that 1 mm of film material reduces the intensity of the X-ray-beam by about 70{\%}, 50{\%} and 40{\%} for Cu-, W- and Mo-tube X-rays, respectively. Monte Carlo simulations were performed to model the energy release as well as the depth dose profiles for the various radiation beams used. These data are considered relevant for dosimetric applications in low energy beams such the high-gradient treatment fields used in monoenergetic microbeam radiation therapy (MRT) with synchrotron radiation as well as in brachytherapy with low energy sources, for instance 169Yb.",
author = "D'Oca, {Maria Cristina} and Giorgio Collura and Leonardo Abbene and Fabio Principato and Maurizio Marrale and Antonio Bartolotta and Marrale and Collura and Bartolotta and D'Oca and Francesco D'Errico and Francesco D'Errico",
year = "2019",
language = "English",
volume = "459",
pages = "1--6",
journal = "NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION B, BEAM INTERACTIONS WITH MATERIALS AND ATOMS",
issn = "0168-583X",

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TY - JOUR

T1 - Alanine films for EPR dosimetry of low-energy (1–30 keV) X-ray photons

AU - D'Oca, Maria Cristina

AU - Collura, Giorgio

AU - Abbene, Leonardo

AU - Principato, Fabio

AU - Marrale, Maurizio

AU - Bartolotta, Antonio

AU - Marrale, null

AU - Collura, null

AU - Bartolotta, null

AU - D'Oca, null

AU - D'Errico, Francesco

AU - D'Errico, Francesco

PY - 2019

Y1 - 2019

N2 - L-alpha-alanine has aroused considerable interest for use in radiation EPR dosimetry and has been formally accepted as a secondary standard for high-dose (kGy) and transfer dosimetry of high-energy photons and electrons. In this work, we extended the investigation of the energy response of alanine EPR films in the low energy range for X-photons (1–30 keV). Electron Paramagnetic Resonance (EPR) measurements were performed on Kodak BioMax alanine films exposed to low-energy X-rays from a Cu-, W- and Mo-targets tube operating at voltages up to 30 kV. Films were chosen because of the low penetration of the soft X-rays used. The response of alanine to low-energy X-rays was characterized experimentally and the relative response (with respect to high energy photons) was found to be between 0.8 and 0.9 for Cu- and W-tube X-rays, and 1.0 for Mo-tube X-rays. The attenuation profiles were investigated and it was found that 1 mm of film material reduces the intensity of the X-ray-beam by about 70%, 50% and 40% for Cu-, W- and Mo-tube X-rays, respectively. Monte Carlo simulations were performed to model the energy release as well as the depth dose profiles for the various radiation beams used. These data are considered relevant for dosimetric applications in low energy beams such the high-gradient treatment fields used in monoenergetic microbeam radiation therapy (MRT) with synchrotron radiation as well as in brachytherapy with low energy sources, for instance 169Yb.

AB - L-alpha-alanine has aroused considerable interest for use in radiation EPR dosimetry and has been formally accepted as a secondary standard for high-dose (kGy) and transfer dosimetry of high-energy photons and electrons. In this work, we extended the investigation of the energy response of alanine EPR films in the low energy range for X-photons (1–30 keV). Electron Paramagnetic Resonance (EPR) measurements were performed on Kodak BioMax alanine films exposed to low-energy X-rays from a Cu-, W- and Mo-targets tube operating at voltages up to 30 kV. Films were chosen because of the low penetration of the soft X-rays used. The response of alanine to low-energy X-rays was characterized experimentally and the relative response (with respect to high energy photons) was found to be between 0.8 and 0.9 for Cu- and W-tube X-rays, and 1.0 for Mo-tube X-rays. The attenuation profiles were investigated and it was found that 1 mm of film material reduces the intensity of the X-ray-beam by about 70%, 50% and 40% for Cu-, W- and Mo-tube X-rays, respectively. Monte Carlo simulations were performed to model the energy release as well as the depth dose profiles for the various radiation beams used. These data are considered relevant for dosimetric applications in low energy beams such the high-gradient treatment fields used in monoenergetic microbeam radiation therapy (MRT) with synchrotron radiation as well as in brachytherapy with low energy sources, for instance 169Yb.

UR - http://hdl.handle.net/10447/373609

UR - https://www.journals.elsevier.com/nuclear-instruments-and-methods-in-physics-research-section-b-beam-interactions-with-materials-and-atoms

M3 - Article

VL - 459

SP - 1

EP - 6

JO - NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION B, BEAM INTERACTIONS WITH MATERIALS AND ATOMS

JF - NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION B, BEAM INTERACTIONS WITH MATERIALS AND ATOMS

SN - 0168-583X

ER -