Ageing: From inflammation to cancer

Roberto Monastero, Giulia Accardi, Ferdinando Nicoletti, Giulia C. Leonardi, Massimo Libra

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.
Original languageEnglish
Pages (from-to)1-7
Number of pages7
Publication statusPublished - 2018

All Science Journal Classification (ASJC) codes

  • Immunology
  • Ageing

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