A retrospective study of the characterization of Rickettsia species in ticks collected from humans

Antonio Cascio, Salvatore Scimeca, Valeria Blanda, Rosalia D'Agostino, José De La Fuente, Francesco La Russa, Kety Randazzo, Elisabetta Giudice, Santo Caracappa, Alessandra Torina, Mauro Francesco La Russa, Santo Caracappa, Valeria Blanda

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13 Citations (Scopus)

Abstract

Rickettsiae (family Rickettsiaceae, order Rickettsiales) are obligate intracellular bacteria transmitted by arthropod vectors. Several Rickettsia species causing vector-borne rickettsioses belong to the spotted fever group (SFG). Traditionally, Rickettsia conorii has been considered as the main etiologic agent of Mediterranean spotted fever. However, the molecular characterization of rickettsiae allowed identifying other species involved in spotted fever in the Mediterranean region. In this study, 42 ticks collected from humans were subjected to morphological identification and molecular characterization of Rickettsia species potentially involved in human rickettsiosis in Sicily. Fourteen ticks positive to at least two Rickettsia spp. molecular markers were used in the study. Identified Rickettsia spp. included R. conorii, found in Rhipicephalus sanguineus sensu lato and Rhipicephalus turanicus, Rickettsia aeschlimannii found in Hyalomma marginatum, Hyalomma lusitanicum, Dermacentor marginatus and Ixodes ricinus, Rickettsia massiliae found in R. turanicus and R. sanguineus s.l., and Rickettsia slovaca found in D. marginatus and R. sanguineus s.l. Our results showed a great variety of zoonotic Rickettsia spp. in ticks collected from humans in Sicily. The Rickettsia spp. reported in this study were identified in previously recognized or new potential tick vectors in Europe, highlighting the risk of infection by different Rickettsia spp. for humans bitten by ticks in Sicily.
Original languageEnglish
Pages (from-to)610-614
Number of pages5
JournalTicks and Tick-borne Diseases
Volume8
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Insect Science
  • Infectious Diseases

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    Cascio, A., Scimeca, S., Blanda, V., D'Agostino, R., De La Fuente, J., La Russa, F., Randazzo, K., Giudice, E., Caracappa, S., Torina, A., La Russa, M. F., Caracappa, S., & Blanda, V. (2017). A retrospective study of the characterization of Rickettsia species in ticks collected from humans. Ticks and Tick-borne Diseases, 8, 610-614.