TY - JOUR
T1 - A Case of Follicular Tumor of Uncertain Malignant Potential (FT-UMP) with Glomeruloid Features Showing Capsular Mucinous Degeneration
AU - Valerio, Maria Rosaria
AU - Graceffa, Giuseppa
AU - Mondello, Andrea
AU - Florena, Ada Maria
AU - Cabibi, Daniela
AU - Giannone, Antonino Giulio
AU - Cipolla, Calogero
PY - 2021
Y1 - 2021
N2 - The most recent revision of the World Health Organization (WHO) Classification of Tumours of Endocrine Organs introduced a new variant of follicular thyroid carcinoma (FTC). It is characterized by a "glomeruloid" architectural pattern of growth. We present a case of follicular tumor with glomeruloid features, with Alcian Blue positive mucinous stromal degeneration in foci of questionable capsular microinvasion. At our knowledge, this the second case of glomeruloid follicular tumor in the literature and the first case in which Alcian Blue staining was used to investigate capsular invasion. Moreover, RAS mutation further supports that this is a variant of follicular tumor with uncertain malignant potential.
AB - The most recent revision of the World Health Organization (WHO) Classification of Tumours of Endocrine Organs introduced a new variant of follicular thyroid carcinoma (FTC). It is characterized by a "glomeruloid" architectural pattern of growth. We present a case of follicular tumor with glomeruloid features, with Alcian Blue positive mucinous stromal degeneration in foci of questionable capsular microinvasion. At our knowledge, this the second case of glomeruloid follicular tumor in the literature and the first case in which Alcian Blue staining was used to investigate capsular invasion. Moreover, RAS mutation further supports that this is a variant of follicular tumor with uncertain malignant potential.
UR - http://hdl.handle.net/10447/503553
M3 - Article
SN - 2090-679X
VL - 2021
SP - 1
EP - 4
JO - CASE REPORTS IN PATHOLOGY
JF - CASE REPORTS IN PATHOLOGY
ER -