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Author

  • Francesco Ciccia
2018

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy

Ciccia, F., Triolo, G., Guggino, G., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Di Bartolomeo, S., Panzera, N., Giacomelli, R. & Cipriani, P., 2018, In : ARTHRITIS RESEARCH & THERAPY. 20, p. 223- 24 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Cardiovascular disease in primary sjögren’s syndrome

Guggino, G., Ciccia, F., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Giacomelli, R. & Cipriani, P., 2018, In : Reviews on Recent Clinical Trials. 13, p. 164-169 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

CD3 immunohistochemistry is helpful in the diagnosis of giant cell arteritis

Ferrante, A., Guggino, G., Ciccia, F., Rizzo, A., Cavazza, A. & Salvarani, C., 2018, In : Rheumatology. 57, p. 1377-1380 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Downregulation of miRNA17-92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis

Guggino, G., Dieli, F., Alessandro, R., Saieva, L., Ciccia, F., La Manna, M. P., Caccamo, N. R., La Manna, M. P., Orlando, V., Ruscitti, P., Dieli, F., Caccamo, N., Giacomelli, R., Cipriani, P. & Orlando, V., 2018, In : ARTHRITIS RESEARCH & THERAPY. 20, p. 236- 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Histopathology of the gut in rheumatic diseases

Ferrante, A., Guggino, G., Ciccia, F. & Rizzo, A., 2018, In : Reumatismo. 70, p. 178-186 9 p.

Research output: Contribution to journalArticle

Interleukin-25 Axis Is Involved in the Pathogenesis of Human Primary and Experimental Murine Sjögren's Syndrome

Ciccia, F., Saieva, L., Candore, G., Triolo, G., Dieli, F., Guggino, G., Di Liberto, D., Alessandro, R., Raimondo, S., Lin, X., Rizzo, A., Ruscitti, P., Xiao, F., Giacomelli, R., Cipriani, P. & Lu, L., 2018, In : ARTHRITIS & RHEUMATOLOGY. 70, p. 1265-1275 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Intestinal Involvement in Kawasaki Disease

Saporito, L., Colomba, C., Ciccia, F., Di Carlo, P., Cascio, A., Corsello, G., Serra, N., Medaglia, A. A. & La Placa, S., 2018, In : Journal of Pediatrics. 202, p. 186-193-193 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Pathogenesis of polymyalgia rheumatica

Guggino, G., Ferrante, A., Triolo, G. & Ciccia, F., 2018, In : Reumatismo. 70, p. 10-17 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pro-inflammatory CX3CR1+ CD59+ TL1A+ IL-23+ monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

Di Liberto, D., Ciccia, F., Guggino, G., Alessandro, R., Saieva, L., Dieli, F., Saieva, L., Haroon, N., Thomas, R., Ranganathan, V., Rahman, A., Dieli, F., Zeng, M., Rahman, A., Di Liberto, D., Alessandro, R., Baeten, D., Giacomelli, R. & Cipriani, P., 2018, In : ARTHRITIS & RHEUMATOLOGY. 15 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis

Ciccia, F., Guggino, G., Ferrante, A., Guggino, G., Ciccia, F. & Ferrante, A., 2018, In : Frontiers in Medicine. 5, p. 1-6 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Sclerostin and antisclerostin antibody serum levels predict the presence of axial spondyloarthritis in patients with inflammatory bowel disease

Triolo, G., Guggino, G., Ciccia, F., Spadoni, T., Guggino, G., Svegliati, S., Triolo, G., Gabrielli, A., Skrami, E., Avellini, C., Rossini, M., Benfaremo, D., Ciferri, M., Farinelli, A., Bolognini, L., Ciccia, F., Gesuita, R., Luchetti, M. M. & Rossini, M., 2018, In : THE JOURNAL OF RHEUMATOLOGY. 45, p. 630-637 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

T2-mapping of the sacroiliac joints at 1.5 Tesla: a feasibility and reproducibility study

Lagalla, R., Albano, D., Galia, M., Ciccia, F., Midiri, M., Sconfienza, L. M., Cuocolo, R., Chianca, V., Brunetti, A. & Bignone, R., 2018, In : Skeletal Radiology. 47, p. 1691-1696 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The emerging role of IL-1 inhibition in patients affected by rheumatoid arthritis and diabetes

Guggino, G., Ciccia, F., Triolo, G., Liakouli, V., Carubbi, F., Di Benedetto, P., Alvaro, S., Ruscitti, P., Berardicurti, O., Giacomelli, R. & Cipriani, P., 2018, In : Reviews on Recent Clinical Trials. 13, p. 210-214 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

β-amyloid wall deposit of temporal artery in subjects with spontaneous intracerebral haemorrhage.

Pinto, A., Corpora, F., Pecoraro, R., Maida, C. D., Tuttolomondo, A., Giannone, A. G., Ciccia, F., Di Raimondo, D., Simonetta, I., Graziano, F., Rizzo, A., Cirrincione, A., Orlando, E. & Portelli, F., 2018, In : Oncotarget. 9, p. 34699-34707 9 p.

Research output: Contribution to journalBook/Film/Article review

2017

Adalimumab efficacy in enteropathic spondyloarthritis: A 12-mo observational multidisciplinary study

Triolo, G., Ciccia, F., Gabrielli, A., Rossini, M., Benfaremo, D., Mosca, P., Ciferri, M., Farinelli, A., Bolognini, L. & Luchetti, M. M., 2017, In : World Journal of Gastroenterology. 23, p. 7139-7149 11 p.

Research output: Contribution to journalBook/Film/Article review

7 Citations (Scopus)

Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?

Guggino, G., Triolo, G., Ciccia, F., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Giacomelli, R. & Cipriani, P., 2017, In : Expert Review of Clinical Immunology. 13, p. 1041-1047 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Brief Report: Functional Interaction of Endoplasmic Reticulum Aminopeptidase 2 and HLAâB27 Activates the Unfolded Protein Response

Ciccia, F., Alessandro, R., Triolo, G., Guggino, G., Zhang, Z., Haroon, N., Abdullah, H., Yee, K., Zeng, F. & Silverberg, M. S., 2017, In : ARTHRITIS & RHEUMATOLOGY. 69, p. 1009-1015 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity

Guggino, G., Alessandro, R., Priori, R., Ciccia, F., Triolo, G., Colasanti, T., Barbati, C., Rizzo, A., Astorri, E., Pendolino, M., Minniti, A., Finucci, A., Vomero, M., Ortona, E., Pierdominici, M., Priori, R., Ortona, E., Valesini, G., Malorni, W., Alessandri, C. & 1 others, Conti, F., 2017, In : ARTHRITIS RESEARCH & THERAPY. 19, p. 178- 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Clinical benefit of vedolizumab on articular manifestations in patients with active spondyloarthritis associated with inflammatory bowel disease

Cottone, M., Ciccia, F., Cottone, M., Renna, S., Orlando, R., Rizzo, A., Macaluso, F. S., Orlando, A., Orlando, A., Macaluso, F. S., Orlando, R. & Renna, S., 2017, In : Annals of the Rheumatic Diseases. 76, p. e31-e31 2 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis

Saieva, L., Ciccia, F., Triolo, G., Alessandro, R., Guggino, G., Rizzo, A., Di Benedetto, P., Cypers, H., Elewaut, D., Stampone, T., Milling, S., Luchetti, M. M. & Fasano, A., 2017, In : Annals of the Rheumatic Diseases. 76, p. 1123-1132 10 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Gut inflammation in spondyloarthritis

Guggino, G., Ferrante, A., Ciccia, F. & Rizzo, A., 2017, In : BAILLIERE'S BEST PRACTICE & RESEARCH: CLINICAL RHEUMATOLOGY. 31, p. 863-876 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

H-ferritin and proinflammatory cytokines are increased in the bone marrow of patients affected by macrophage activation syndrome

Ciccia, F., Guggino, G., Triolo, G., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Giacomelli, R. & Cipriani, P., 2017, In : Clinical and Experimental Immunology. 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
10 Citations (Scopus)

Increased expression of interleukin-22 in patients with giant cell arteritis

Ciccia, F., Alessandro, R., Belloni, L., Moramarco, A., Rizzo, A., Bonacini, M., Cimino, L., Parmeggiani, M., Zerbini, A., Croci, S., Cimino, L., Muratore, F., Cavazza, A., Boiardi, L. & Salvarani, C., 2017, In : Rheumatology. 57, p. 64-72 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Interleukin-9 over-expression and T helper 9 polarization in systemic sclerosis patients.

Guggino, G., Ciccia, F., Gambino, C. M., Candore, G., Triolo, G., Dieli, F., Rizzo, A., Ruscitti, P., Giacomelli, R., Cipriani, P. & Sireci, G., 2017, In : Clinical and Experimental Immunology. 190, 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

International consensus: What else can we do to improve diagnosis and therapeutic strategies in patients affected by autoimmune rheumatic diseases (rheumatoid arthritis, spondyloarthritides, systemic sclerosis, systemic lupus erythematosus, antiphospholipid syndrome and Sjogren's syndrome)?: The unmet needs and the clinical grey zone in autoimmune disease management

Ciccia, F., Priori, R., Triolo, G., Liakouli, V., Quartuccio, L., Alunno, A., Vettori, S., Ursini, F., Massaro, L., Cervera, R., Meroni, P., Puppo, F., Sarzi-Puttini, P., Bartoloni-Bocci, E., Shoenfeld, Y., Navarini, L., Pendolino, M., Carubbi, F., Di Benedetto, P., Ruscitti, P. & 34 others, Gatto, M., Minniti, A., Berardicurti, O., Russo, B., Somarakis, G. A., Spinelli, F. R., Gandolfo, S., Cervera, R., Doria, A., Margiotta, D. P. E., Tinazzi, E., Grembiale, R. D., Favalli, E. G., Lories, R., Baldini, C., Lubrano, E., Prete, M., Pers, J-O., Perosa, F., Cauli, A., Ruffatti, A., Priori, R., Valesini, G., Giacomelli, R., Vitali, C., Afeltra, A., Cipriani, P., Drosos, A. A., Lunardi, C., Tzioufas, A. G., De Vita, S., Conti, F., Valentini, G. & Russo, B., 2017, In : Autoimmunity Reviews. 16, p. 911-924 14 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Interstitial lung disease in systemic sclerosis: current and future treatment

Guggino, G., Triolo, G., Ciccia, F., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Di Bartolomeo, S., Giacomelli, R. & Cipriani, P., 2017, In : Rheumatology International. 37, p. 853-863 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Macrophage Migration Inhibitory Factor Induces Inflammation and Predicts Spinal Progression in Ankylosing Spondylitis

Ciccia, F., Guggino, G., Haroon, N., Gracey, E., Ranganathan, V., Sari, I., Zeng, F. & Muralitharan, J., 2017, In : ARTHRITIS & RHEUMATOLOGY. 69, p. 1796-1806 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

New insights into the pathogenesis of giant cell arteritis

Ferrante, A., Guggino, G., Ciccia, F., Triolo, G., Rizzo, A., Croci, S., Cavazza, A. & Salvarani, C., 2017, In : Autoimmunity Reviews. 16, p. 675-683 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance identifies very early cardiac involvement in systemic sclerosis patients of recent onset

Ciccia, F., Guggino, G., Triolo, G., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Di Sibio, A., Gennarelli, A., Berardicurti, O., Radchenko, G., Splendiani, A., Masciocchi, C., Di Cesare, E., Giacomelli, R. & Cipriani, P., 2017, In : International Journal of Rheumatic Diseases. 20, p. 1247-1260 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Prevalence of type 2 diabetes and impaired fasting glucose in patients affected by rheumatoid arthritis

Guggino, G., Triolo, G., Ciccia, F., Liakouli, V., Ursini, F., Carubbi, F., Ruscitti, P., Berardicurti, O., De Sarro, G., Grembiale, R., Giacomelli, R. & Cipriani, P., 2017, In : MEDICINE. 96, p. e7896- 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Psoriatic Arthritis

Triolo, G., Ciccia, F. & Rizzo, A., 2017, In : New England Journal of Medicine. 376, p. 2094-2095 2 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Reply

Guggino, G., Alessandro, R., Raimondo, S. & Ciccia, F., 2017, In : ARTHRITIS & RHEUMATOLOGY. 69, p. 473-475 3 p.

Research output: Contribution to journalLetter

2016

Adult-onset Still's disease: Evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers

Guggino, G., Triolo, G., Ciccia, F., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Iacono, D., Masedu, F., Giacomelli, R., Cipriani, P., Valenti, M. & Valentini, G., 2016, In : BMC Medicine. 14, p. 194- 11 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Adult-onset Still’s disease: an Italian multicentre retrospective observational study of manifestations and treatments in 245 patients

Priori, R., Triolo, G., Ciccia, F., Alessandri, E., Govoni, M., Colaci, M., Alivernini, S., Caso, F., Bagnari, V., Ferraccioli, G., Ferri, C., Carli, L., Ruscitti, P., Galozzi, P., Piazza, I., Iacono, D., Montecucco, C. M., Rossi, S., Lomonaco, A., D’Ascanio, A. & 17 others, Laselva, G., Montecucco, C. M., Sfriso, P., Iannone, F., Priori, R., Lapadula, G., Galeazzi, M., Punzi, L., Valesini, G., Adami, S., Giacomelli, R., Bombardieri, S., Scarpa, R., Valentini, G., Cutolo, M., Costa, L. & Cantarini, L., 2016, In : Clinical Rheumatology. 35, p. 1683-1689 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Autophagy in the pathogenesis of ankylosing spondylitis

Ciccia, F., Haroon, N. & Ciccia, F., 2016, In : Clinical Rheumatology. 35, p. 1433-1436 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Clinical efficacy of α4 integrin block with natalizumab in ankylosing spondylitis

Galia, M., Guggino, G., Ciccia, F., Triolo, G., Rizzo, A. & Bignone, R., 2016, In : Annals of the Rheumatic Diseases. 75, p. 2053-2054-2054 2 p.

Research output: Contribution to journalLetter

9 Citations (Scopus)

Ectopic expression of CXCL13, BAFF, APRIL and LT-ß is associated with artery tertiary lymphoid organs in giant cell arteritis

Guggino, G., Ciccia, F., Triolo, G., Alessandro, R., Raimondo, S., Rizzo, A., Cannizzaro, A., Croci, S., Cavazza, A., Salvarani, C. & Cannizzaro, A., 2016, In : Annals of the Rheumatic Diseases. p. annrheumdis-2016-209217- 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
3 Citations (Scopus)

H-ferritin and CD68+/H-ferritin+ monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease

Triolo, G., Ciccia, F., Guggino, G., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Di Bartolomeo, S., Giacomelli, R. & Cipriani, P., 2016, In : Clinical and Experimental Immunology. 186, p. 30-38 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

Triolo, G., Guggino, G., Ciccia, F., Liakouli, V., Carubbi, F., Di Benedetto, P., Alvaro, S., Ruscitti, P., Berardicurti, O., Giacomelli, R. & Cipriani, P., 2016, In : Expert Review of Clinical Immunology. 12, p. 849-855 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Interleukin (IL)-9/IL-9R axis drives γδ T cells activation in psoriatic arthritis patients

Lo Pizzo, M., Dieli, F., Guggino, G., Di Liberto, D., Ciccia, F., Ferrante, A., Triolo, G., Sireci, G., Ruscitti, P., Dieli, F., Lo Pizzo, Sireci, G., Di Liberto, D., Fourniè, J. J., Giacomelli, R. & Cipriani, P., 2016, In : Clinical and Experimental Immunology. 186, p. 277-283 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Interleukin-9 and T helper type 9 cells in rheumatic diseases

Ferrante, A., Guggino, G., Ciccia, F., Triolo, G., Giacomelli, R. & Cipriani, P., 2016, In : Clinical and Experimental Immunology. 185, p. 125-132 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Intestinal dysbiosis and innate immune responses in axial spondyloarthritis

Triolo, G., Ciccia, F., Ferrante, A. & Triolo, G., 2016, In : Current Opinion in Rheumatology. 28, p. 352-358 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
8 Citations (Scopus)

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue

Guggino, G., Ciccia, F., Mchugh, K., Rysnik, O., Van Tok, M., Kollnberger, S., Van Duivenvoorde, L., Baeten, D., Bowness, P. & Taurog, J., 2016, In : Journal of Autoimmunity. 70, p. 12-21 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Perivascular cells in diffuse cutaneous systemic sclerosis overexpress activated ADAM12 and are involved in myofibroblast transdifferentiation and development of fibrosis

Ciccia, F., Triolo, G., Guggino, G., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Zazzeroni, F., Alesse, E., Giacomelli, R. & Cipriani, P., 2016, In : THE JOURNAL OF RHEUMATOLOGY. 43, p. 1340-1349 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers

Guggino, G., Ciccia, F., Liakouli, V., Carubbi, F., Di Benedetto, P., Ruscitti, P., Berardicurti, O., Di Bartolomeo, S., Masedu, F., Giacomelli, R., Cipriani, P. & Valenti, M., 2016, In : Autoimmunity Reviews. 16, p. 16-21 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)