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Author

  • Giuseppe Montalto
2020

Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells

Montalto, G., Notarbartolo Di Villarosa, M., Cervello, M., Ramazzotti, G., Martelli, A. M., Candido, S., Bueno-Silva, B., Ratti, S., Matias De Alencar, S., Gizak, A., Lertpiriyapong, K., Rakus, D., Rosalen, P. L., Libra, M., Matias De Alencar, S., Akula, S. M., Steelman, L. S., Falasca, M., Mccubrey, J. A., Murata, R. M. & 4 others, Cocco, L., Montalto, G., Follo, M. Y. & Abrams, S. L., 2020, In : Advances in Biological Regulation. 75, p. 1-15 15 p.

Research output: Contribution to journalArticle

New landscapes and horizons in hepatocellular carcinoma therapy

Emma, M. R., Montalto, G., Belmonte, B., Soresi, M., Giannitrapani, L., Cervello, M., Augello, G., Emma, M. R., Giannitrapani, L., Cusimano, A., Akula, S. M., Steelman, L. S., Mccubrey, J. A., Montalto, G. & Abrams, S. L., 2020, In : Aging. 12, p. 3053-3094 42 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Targeting NUPR1 with the small compound ZZW-115 is an efficient strategy to treat hepatocellular carcinoma

Montalto, G., Giannitrapani, L., Cervello, M., Xia, Y., Fraunhoffer, N., Santofimia-Castaño, P., Barea, D., Zhou, Z., Lan, W., Huang, C., Iovanna, J. & Peng, L., 2020, In : Cancer Letters. 486, p. 8-17 10 p.

Research output: Contribution to journalArticle

The Changing Epidemiology of Hepatocellular Carcinoma :  Experience of a Single Center

Soresi, M., Brancatelli, G., Giannitrapani, L., Licata, A., Montalto, G., Galia, M., Galati, L., Schiavone, C., Pipitone, E., Zerbo, M., Minissale, M. G. & Amodeo, S., 2020, In : BioMed Research International. 2020, p. 1-9 9 p.

Research output: Contribution to journalArticle

2019

Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells

Montalto, G., Cervello, M., Mao, W., Martelli, A. M., Candido, S., Ratti, S., Gizak, A., Lertpiriyapong, K., Rakus, D., Rosalen, P. L., Libra, M., Steelman, L. S., Mccubrey, J. A., Lombardi, P., Murata, R. M., Cocco, L., Montalto, G., Follo, M. Y. & Abrams, S. L., 2019, In : Advances in Biological Regulation. 71, p. 172-182 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells

Montalto, G., Cervello, M., Mao, W., Ramazzotti, G., Martelli, A. M., Candido, S., Bueno-Silva, B., Ratti, S., Lin, H-L., Gizak, A., Lertpiriyapong, K., Rakus, D., Rosalen, P. L., Libra, M., Matias De Alencar, S., Akula, S. M., Steelman, L. S., Mccubrey, J. A., Lombardi, P., Murata, R. M. & 4 others, Montalto, G., Follo, M. Y., Abrams, S. L. & Ramazzotti, G., 2019, In : Advances in Biological Regulation. 19 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Citations (Scopus)
3 Citations (Scopus)

Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals

Montalto, G., Cervello, M., Mao, W., Martelli, A. M., Candido, S., Bueno-Silva, B., Ratti, S., Lin, H-L., Gizak, A., Lertpiriyapong, K., Rakus, D., Rosalen, P. L., Libra, M., De Alencar, S. M., Akula, S. M., Steelman, L. S., Mccubrey, J. A., Lombardi, P., Murata, R. M., Cocco, L. & 3 others, Montalto, G., Follo, M. Y. & Abrams, S. L., 2019, In : Advances in Biological Regulation. 72, p. 22-40 19 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1 Citation (Scopus)
1 Citation (Scopus)

Mortality rate and risk factors for gastrointestinal bleeding in elderly patients

Montalto, G., Licata, A., Barbagallo, M., Dominguez Rodriguez, L. J., Corrao, S., Cocita, F., Plances, L., Malerba, V. & Beneduce, V., 2019, In : European Journal of Internal Medicine. 61, p. 54-61-61 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Need for Deprescribing in Hospital Elderly Patients Discharged with a Limited Life Expectancy: The REPOSI Study

Licata, A., Montalto, G., Licata, G., Barbagallo, M., Dominguez Rodriguez, L. J., Cocita, F., Plances, L., Malerba, V. & Beneduce, V., 2019, In : Medical Principles and Practice. 28, p. 501-508 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Patterns of infections in older patients acutely admitted to medical wards: data from the REPOSI register

Licata, A., Dominguez Rodriguez, L. J., Corrao, S., Montalto, G., Barbagallo, M., Montalto, F. A., Cocita, F., Plances, L., Malerba, V. & Beneduce, V., 2019, In : Internal and Emergency Medicine. 14, p. 1347-1352 6 p.

Research output: Contribution to journalLetter

Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients

Barbagallo, M., Corrao, S., Licata, G., Montalto, G., Licata, A., Dominguez Rodriguez, L. J., Montalto, F. A., Cocita, F., Plances, L., Malerba, V. & Beneduce, V., 2019, In : European Journal of Internal Medicine. 68, p. e7-e11 5 p.

Research output: Contribution to journalLetter

RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma

Emma, M. R., Montalto, G., Cervello, M., Augello, G., Emma, M. R., Azzolina, A., Cusimano, A., Akula, S. M., Steelman, L. S., Mccubrey, J. A., Montalto, G. & Abrams, S. L., 2019, In : Expert Opinion on Therapeutic Targets. 23, p. 915-929 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma

Cassata, G., Montalto, G., Emma, M. R., Gulino, A., Belmonte, B., Cervello, M., Cassata, G., Augello, G., Emma, M. R., Puleio, R., Azzolina, A., Mongiovì, S., Cusimano, A., Mccubrey, J. A., Strom, S. C., Montalto, G., Gramignoli, R., Cusimano, A. & Augello, G., 2019, In : International Journal of Cancer. 144, p. 2613-2624 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2018

Association between MICA Gene Variants and the Risk of Hepatitis C Virus-Induced Hepatocellular Cancer in a Sicilian Population Sample

Montalto, G., Giannitrapani, L., Balasus, D., Emma, M. R., Cervello, M., Augello, G., Balasus, D., Emma, M. R., Agliastro, R., Fusilli, C., Montalto, G., Mazza, T., Augello, G. & Agliastro, R., 2018, In : OMICS. 22, p. 274-282 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Corrigendum to “Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV” [J Hepatol 68 (2018) 33–41](S0168827817322596)(10.1016/j.jhep.2017.08.019)

Montalto, G., Petta, S., Calvaruso, V., Craxi, A., Rosato, S., Giorgini, A. M., Manthena, S., Andreone, Amoruso, Cima, Mallano, Masarone, M., Bristot, L., Brunetto, M. R., Castelli, Angelico, M., Critelli, R. M., Gori, A., Russo, F. P., Gaeta, G. B. & 69 others, Milella, M., Karampatou, A., Ieluzzi, D., Villa, E., Troshina, G., Filomia, R., Vella, S., Strazzulla, A., Dallio, Dissegna, Turco, L., Zanetto, A., Guarino, M., Zuin, M., Chessa, L., Tagliavini, S., Gonzalez, Y. S., Pasetto, M. C., Raimondo, G., Simonetti, Danieli, E., Bigliotti, D'Ambrosio, F., Han, X., Goldstein, A. S., De Leonardis, F., Gemma, Finati, Di Fine, Tamburrini, Cappelletti, Ludovisi, Puoti, Brancaccio, G., Persico, M., Alessandro, Lazzarini, Quaranta, Alessandro, Framarin, Zaltron, Gragnani, Kondili, L. A., Coco, B., Trenti, T., Falzano, L., Morisco, F., Weimer, L. E., Strazzabosco, M., Ciancio, A., Torti, C., Toniutto, La Marca, A., Coppola, C., Mazzella, G., Neri, I., Rosina, F., Fattovich, Mondelli, Zignego, Taliani, G., Baraldi, E., Angarano, G., Persico, M., Bruno, R., Bruno, S., Monti, M., Bao, Y. & Bernabucci, V., 2018, In : Journal of Hepatology. 68, p. 867-867 1 p.

Research output: Contribution to journalComment/debate

Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cellsâPower of nutraceuticals

Montalto, G., Cervello, M., Martelli, A. M., Candido, S., Ratti, S., Gizak, A., Lertpiriyapong, K., Rakus, D., Rosalen, P. L., Libra, M., Steelman, L. S., Mccubrey, J. A., Lombardi, P., Murata, R. M., Cocco, L., Montalto, G. & Abrams, S. L., 2018, In : Advances in Biological Regulation. 67, p. 190-211 22 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Effects of direct-acting antiviral therapy (DAAS) on the ultrasound parameters of portal hypertension

Giannitrapani, L., Soresi, M., Montalto, G., Terranova, A., Capitano, A. R., Puccia, F., Montalto, F. A., Mirarchi, L. & Minissale, M. G., 2018, p. 11-11. 1 p.

Research output: Contribution to conferenceOther

GLP-1 receptor agonists and reduction of cardiometabolic risk: Potential underlying mechanisms

Nikolic, D., Rizzo, M., Patti, A. M., Montalto, G., Rizzo, M., Mcadams, B. S., Cosentino, F., Rizvi, A. A., Rizzo, M. & Mannina, C., 2018, In : BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE. 1864, p. 2814-2821 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Incidence of Hepatocellular Carcinoma in Patients With HCV-Associated Cirrhosis Treated With Direct-Acting Antiviral Agents

Cascio, A., Giannitrapani, L., Distefano, B. M. C., Montalto, G., Licata, A., Calvaruso, V., Petta, S., Di Marco, V., Craxi, A., Cabibbo, G., Camma', C., Averna, A., Tine', F., Latteri, F., Malizia, G., Caccamo, G., Magro, G. A., Barbara, M., Mondello, M. L. & Maimone, S., 2018, In : Gastroenterology. 155, p. 411-421 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals

Ratti, S., Montalto, G., Yang, L. V., Cervello, M., Martelli, A. M., Candido, S., Ratti, S., Lertpiriyapong, K., Rosalen, P. L., Libra, M., Steelman, L. S., Falasca, M., Mccubrey, J. A., Lombardi, P., Murata, R. M., Cocco, L., Montalto, G. & Abrams, S. L., 2018, In : Advances in Biological Regulation. 69, p. 16-34 19 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Metformin influences drug sensitivity in pancreatic cancer cells

Ratti, S., Montalto, G., Cervello, M., Martelli, A. M., Candido, S., Suh, P-G., Ratti, S., Gizak, A., Lertpiriyapong, K., Rakus, D., Rosalen, P. L., Libra, M., Steelman, L., Mccubrey, J. A., Lombardi, P., Murata, R. M., Cocco, L., Montalto, G., Follo, M. Y. & Abrams, S. L., 2018, In : Advances in Biological Regulation. 68, p. 13-30 18 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Natural approaches in metabolic syndrome management

Montalto, G., Rizzo, M., Patti, A. M., Nikolic, D., Mannina, C., Giglio, R. V., Castellino, G., Cicero, A. F. G., Toth, P. P., Patti, A. M., Banach, M., Lippi, G., Al-Rasadi, K., Nikolic, D., Giglio, R. V., Rizzo, M., Castellino, G. & Chianetta, R., 2018, In : Archives of Medical Science. 14, p. 422-441 20 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Nontumorous portal vein thrombosis in liver cirrhosis: Possible role of β-blockers

Soresi, M., Montalto, G., Licata, A., Giannitrapani, L., Schiavone, C. & Grana', W., 2018, In : Medical Principles and Practice. 27, p. 466-471 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Pancreatic cancer: risk and preventive factors

Soresi, M., Montalto, G. & Licata, A., 2018, In : Internal and Emergency Medicine. p. 1-3 3 p.

Research output: Contribution to journalArticle

Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells

Emma, M. R., Montalto, G., Cervello, M., Cassata, G., Augello, G., Emma, M. R., Puleio, R., Di Sano, C., Modica, M., Azzolina, A., Cusimano, A., Montalto, G. & Puleio, B., 2018, In : CELL DEATH & DISEASE. 9, p. 28-

Research output: Contribution to journalArticle

11 Citations (Scopus)

Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines

Montalto, G., Cervello, M., Ramazzotti, G., Leng, X., Martelli, A. M., Candido, S., Ove, R., Libra, M., Steelman, L. S., Mccubrey, J. A., Cocco, L., Arlinghaus, R. B., Montalto, G., Russo, S., Chappell, W. H. & Abrams, S. L., 2018, In : Advances in Biological Regulation. 69, p. 43-62 20 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Statins in liver disease: not only prevention of cardiovascular events

Montalto, G., Rizzo, M., Magan-Fernandez, A. & Marchesini, G., 2018, In : EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. 12, p. 743-744 2 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
8 Citations (Scopus)
2017

A phenobarbital overdose: a case report

Giannitrapani, L., Montalto, G., Licata, A., Soresi, M., Serruto, A., Pollaccia, E. & Minissale, M. G., 2017, p. 114-114. 1 p.

Research output: Contribution to conferenceOther

BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC)

Montalto, G., Loncle, C., Benyamine, A., Secq, V., Chrétien, A-S., Castanier, C., Vila-Navarro, E., Blazquez, J-L., Modesti, M., Foucher, E., Gironella, M., Dusetti, N., Dagorn, J-C., Chouaib, S., Iovanna, J. & Olive, D., 2017, In : OncoImmunology. 7, p. e1372080- 14 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

DRUG INDUCED LIVER INJURIES BY TICAGRELORSTATINSINTERACTION: A CASE REPORT

Licata, A., Soresi, M., Montalto, G., Serruto, A., Montalto, F. A. & Minissale, M. G., 2017, p. 117-117. 1 p.

Research output: Contribution to conferenceOther

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

Montalto, G., Yang, L. V., Cervello, M., Martelli, A. M., Dulinska-Litewka, J., Candido, S., Nicoletti, F., Ratti, S., Abrams, S. L., Gizak, A., Lertpiriyapong, K., Scalisi, A., Rakus, D., Rosalen, P. L., Libra, M., Steelman, L. S., Laidler, P., Mccubrey, J. A., Neri, L. M., Lombardi, P. & 4 others, Murata, R. M., Cocco, L., Montalto, G. & Abrams, S. L., 2017, In : Aging. 9, p. 1477-1536 60 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

KIR2DL3 and the KIR ligand groups HLA-A-Bw4 and HLA-C2 predict the outcome of hepatitis B virus infection.

Accardi, G., Di Lorenzo, G., Rubino, R., Colomba, C., Giannitrapani, L., Tuttolomondo, A., Caruso, C., Aiello, A., Montalto, G., Cascio, A., Candore, G., Rizzo, S., Bilancia, M., Di Bona, D., Macchia, Duro, G., Caiaffa, Candore, Rizzo, S. & Caruso, C., 2017, In : Journal of Viral Hepatitis. 24, p. 768-775 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Modeling cost-effectiveness and health gains of a “universal“ versus “prioritized“ hepatitis C virus treatment policy in a real-life cohort

Montalto, G., Craxi, A., Raimondo, G., Vinci, M. L., Cicchetti, A., Kondili, L. A., Nardone, G., Ciancio, A., Chemello, L., Puoti, M., Coppola, C., Rumi, M. G., Foti, G., Massari, M., Zignego, A. L., Taliani, G., Borgia, G., Rosato, S., Andreone, P., Ruggeri, M. & 23 others, Brunetto, M. R., Alberti, A., Blanc, P., Russo, F. P., Ieluzzi, D., Villa, E., Erne, E. M., Madonia, S., Vinci, M., Quaranta, M. G., Romano, F., Ferrari, C., Zuin, M., Chessa, L., Di Leo, A., Gasbarrini, A., Santantonio, T. A., Rolli, F. R., Vella, S., Verucchi, G., Gaeta, G. B., Raimondo, G. & Persico, M., 2017, In : Hepatology. 66, p. 1814-1825-1825 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Modeling cost-effectiveness and health gains of a "universal" versus "prioritized" hepatitis C virus treatment policy in a real-life cohort.

Montalto, G., Craxi, A., Rosato, S., Andreone, P., Ruggeri, M., Brunetto, M. R., Alberti, A., Blanc, P., Russo, F. P., Gaeta, G. B., Ieluzzi, D., Villa, E., Erne, E. M., Vella, S., Gasbarrini, A., Madonia, S., Romano, F., Ferrari, C., Zuin, M., Chessa, L. & 25 others, Di Leo, A., Gasbarrini, A., Foti, G., Rumi, M. G., Santantonio, T. A., Rolli, F. R., Verucchi, G., Vinci, M., Puoti, M., Raimondo, G., Persico, M., Quaranta, M. G., Quaranta, M. G., Cicchetti, A., Kondili, L. A., Nardone, G., Ciancio, A., Chemello, L., Coppola, C., Rumi, M. G., Massari, M., Zignego, A. L., Taliani, G., Borgia, G. & Persico, M., 2017, In : HEPATOLOGY. 66, p. 1814-1825 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation

Balasus, D., Montalto, G., Emma, M. R., Cervello, M., Augello, G., Balasus, D., Emma, M. R., Di Sano, C., Azzolina, A., Cusimano, A., Mccubrey, J. A., Strom, S. C., Montalto, G., Gramignoli, R., Cusimano, A., Di Sano, C. & Augello, G., 2017, In : International Journal of Oncology. 51, p. 533-544 12 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma

Emma, M. R., Montalto, G., Balasus, D., Cervello, M., Augello, G., Balasus, D., Emma, M. R., Azzolina, A., Cusimano, A., Mccubrey, J. A., Montalto, G., Cusimano, A. & Augello, G., 2017, In : Advances in Biological Regulation. 65, p. 59-76 18 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)