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• Ageing: From inflammation to cancer

  Accardi, G., Monastero, R., Nicoletti, F., Leonardi, G. C. & Libra, M., 2018, In: IMMUNITY & AGEING. 15, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Inflammation
  • Neoplasms
  • Biological Phenomena
  • Neoplasm Metastasis
  39 Citations (Scopus)

• Aging successfully: The role of genetics and environment in the era of the aging-boom. potential therapeutic implications

  Accardi, G. & Aiello, A., 2019, In: CURRENT PHARMACEUTICAL DESIGN. 25, p. 4131-4132 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Longevity
  • Healthy Aging
  • Aptitude
  • Health Services Accessibility
  • Population

• Association between γ marker, human leucocyte antigens and killer immunoglobulin-like receptors and the natural course of human cytomegalovirus infection: a pilot study performed in a Sicilian population

  Caruso, C., Candore, G., Colomba, C., Di Bona, D., Accardi, G., Aiello, A., Duro, G., Gambino, C. M., Bilancia, M., Di Bona, D., Macchia, L., Duro, G. & Pandey, J. P., 2018, In: Immunology. 153, p. 523-531 9 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Cytomegalovirus Infections
  • HLA Antigens
  • Population
  • Cytomegalovirus
  9 Citations (Scopus)

• Association between γ marker, human leucocyte antigens and killer immunoglobulin-like receptors and the natural course of human cytomegalovirus infection: a pilot study performed in a Sicilian population

  Aiello, A., Caruso, C., Candore, G., Accardi, G., Colomba, C., Gambino, C. M., Pandey, J. P., Bilancia, M., Di Bona, D., Macchia, L., Duro, G., Di Bona, D. & Duro, G., 2018, In: Immunology. 153, p. 523-531 9 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Cytomegalovirus Infections
  • HLA Antigens
  • Population
  • Cytomegalovirus
  9 Citations (Scopus)

• Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy

  Accardi, G., Aiello, A., Caruso, C., Gambino, C. M., Candore, G., Ferrario, A., Pandey, J. P., Namboodiri, A. M., Maciag, A. & Puca, A. A., 2018, In: IMMUNITY & AGEING. 15, p. 00-00 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunoglobulin Allotypes
  • Italy
  • Longevity
  • Immunoglobulin Subunits
  • Epitopes
  6 Citations (Scopus)

• Autoimmune diseases and 8.1 ancestral haplotype: an update

  Aiello, A., Gambino, C. M., Accardi, G., Caruso, C. & Candore, G., 2018, In: HLA. 92, p. 137-143 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Haplotypes
  • Autoimmune Diseases
  • HLA-B8 Antigen
  • HLA-DR3 Antigen
  • Alleles
  15 Citations (Scopus)

• Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing

  Accardi, G., Caruso, C., Villa, F., Spinelli, C. & Puca, A. A., 2018, In: Mechanisms of Ageing and Development. 174, p. 95-102 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Healthy Aging
  • Aged, 80 and over
  • Epigenomics
  • Longevity
  • Chromatin
  19 Citations (Scopus)

• Chance and Causality in Ageing and Longevity

  Vasto, S., Caruso, C., Accardi, G. & Aiello, A., 2019, Centenarians. An Example of Positive Biology.. p. 1-21 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • causality
  • life-span
  • statistician
  • joint venture
  • life sciences

• Circulating Molecular Chaperones in Subjects with Amnestic Mild Cognitive Impairment and Alzheimer's Disease: Data from the Zabùt Aging Project

  Cefalu', A. B., Monastero, R., Caruso Bavisotto, C., Cappello, F., Restivo, V., Marino Gammazza, A., Accardi, G. & Baschi, R., 2018, In: Journal of Alzheimer's Disease. p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Molecular Chaperones
  • Cognitive Dysfunction
  • Alzheimer Disease
  • Sicily
  • Italy

• Clinical course and genetic susceptibility of primary biliary cirrhosis: Analysis of a prospective cohort

  Grimaudo, S., Almasio, P. L., Licata, A., Craxi, A., Caruso, C., Accardi, G., Costantino, A., Macaluso, F. S., Maida, M. F. & Alessi, N., 2016, In: Hepatitis Monthly. 16

  Research output: Contribution to journal › Article › peer-review

  • Biliary Liver Cirrhosis
  • Genetic Predisposition to Disease
  • HLA-DRB1*07 antigen
  • HLA-DRB1 Chains
  • Disease Progression
  3 Citations (Scopus)

• Dietary inflammatory index and cancer risk in the elderly: A pooled-analysis of Italian case-control studies

  Caruso, C., Accardi, G., Shivappa, N., Di Maso, M., La Vecchia, C., Polesel, J., Fratino, L., Libra, M., Serraino, D., Montella, M. & Hébert, J. R., 2019, In: Nutrition. 63-64, p. 205-210 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Case-Control Studies
  • Elderly
  • Neoplasms
  • Endometrium
  • Italy
  8 Citations (Scopus)

• Dietary Supplements as Surrogate of Mediterranean Diet in Healthy Smoking Subjects

  Di Gaudio, F., Indelicato, S., Accardi, G., Barera, A., Aiello, A., Candore, G., Caruso, C., Monastero, R., Rizzo, C. M., Vasto, S., Vasto, S., Galimberti, D., Italiano, E., Di Gaudio, F. & Caruso, C., 2018, In: Rejuvenation Research. 21, p. 37-43 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mediterranean Diet
  • Dietary Supplements
  • Piper nigrum
  • Antioxidants
  • Oxidative Stress
  2 Citations (Scopus)

• Effect of extra virgin olive oil and table olives on the immuneInflammatory responses: Potential clinical applications

  Caruso, C., Taormina, G., Candore, G., Accardi, G., Gambino, C. M., Mirisola, M. G., Aiello, A., Dara-Guccione, G., Procopio, A. & Dara-Guccione, G., 2018, In: ENDOCRINE, METABOLIC & IMMUNE DISORDERS DRUG TARGETS. 18, p. 14-22 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Olea
  • Olive Oil
  • Functional Food
  • Dietary Supplements
  • Antioxidants
  11 Citations (Scopus)

• Effect of Extra Virgin Olive Oil and Table Olives on the ImmuneInflammatory Responses: Potential Clinical Applications

  Caruso, C., Candore, G., Mirisola, M. G., Taormina, G., Accardi, G., Aiello, A., Gambino, C. M., Dara-Guccione, G. & Procopio, A., 2018, In: ENDOCRINE, METABOLIC & IMMUNE DISORDERS DRUG TARGETS. 18, p. 14-22- 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Olea
  • Olive Oil
  • Functional Food
  • Dietary Supplements
  • Inflammation
  11 Citations (Scopus)

• Effects of nutraceuticals of Mediterranean diet on aging and longevity

  Caruso, C., Candore, G., Aiello, A. & Accardi, G., 2020, The Mediterranean Diet -2nd Edition- An Evidence-Based Approach. 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Mediterranean diet
  • functional foods
  • bioactive compounds
  • glycemic index
  • animal proteins

• Fibres as functional foods and the effects on gut hormones: The example of β-glucans in a single arm pilot study

  Ruisi, P., Vasto, S., Baldassano, S., Buscemi, S., Caruso, C., Accardi, G., Aiello, A., Di Miceli, G., Candore, G., Vasto, S., Galimberti, D. & Caruso, C., 2018, In: Journal of Functional Foods. 47, p. 264-269 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Glucans
  • Functional Food
  • glucans
  • functional foods
  • dietary fiber
  2 Citations (Scopus)

• Genetic Signatures of Centenarians: Implications for Achieving Successful Aging

  Caruso, C., Aiello, A., Accardi, G., Ciaglia, E., Cattaneo, M., Puca, A. & Cattaneo, M., 2019, In: CURRENT PHARMACEUTICAL DESIGN. 25, p. 4133-4138 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over
  • Longevity
  • Alleles
  • Medical Economics
  • Multifactorial Inheritance
  5 Citations (Scopus)

• Genotypic and phenotypic aspects of longevity: results from a Sicilian survey and implication for the prevention and the treatment of age-related diseases

  Mazzucco, W., Cristaldi, L., Caruso, C., Vasto, S., Gambino, C. M., Aiello, A., Candore, G., Accardi, G., Ligotti, M. E., Vasto, S., Cusimano, R., Bona, D. D., Galimberti, D., Cristaldi, L., Bona, D. D., Duro, G., Caruso, C., Di Bona, D., Duro, G., Cusimano, R. & 1 others, Aprile, S., 2019, In: CURRENT PHARMACEUTICAL DESIGN. 25, p. 228-235 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Longevity
  • Life Style
  • Sicily
  • Frailty
  • Translational Medical Research
  7 Citations (Scopus)

• HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute ischemic stroke

  Aiello, A., Di Raimondo, D., Pecoraro, R., Casuccio, A., Tuttolomondo, A., Pinto, A., Accardi, G., Maida, C. D., Simonetta, I., Della Corte, V., Caruso, C., Arnao, V., Pecoraro, R., Squatrito, R., Di Bona, D., Di Bona, D. & Clemente, G., 2019, In: Journal of Neuroinflammation. 16, 15 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • HLA Antigens
  • Stroke
  • Genes
  • Alleles
  7 Citations (Scopus)

• HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute viral encephalitis

  Maida, C. D., Cascio, A., Arnao, V., Casuccio, A., Tuttolomondo, A., Accardi, G., Caruso, C., Colomba, C., Della Corte, V., Pinto, A., Di Raimondo, D., Pecoraro, R., Simonetta, I., Aiello, A., Ragonese, P., Di Bona, D., Di Bona, D. & Clemente, G., 2018, In: Oncotarget. 9, p. 17523-17532 10 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Viral Encephalitis
  • HLA-A Antigens
  • HLA-Bw4 antigen
  • Encephalitis
  5 Citations (Scopus)

• HLA-C1 ligands are associated with increased susceptibility to systemic lupus erythematosus

  Aiello, A., Ferrante, A., Guggino, G., Candore, G., Gambino, C. M., Caruso, C., Accardi, G., Zinellu, A., Di Bona, D., Duro, G., Carru, C., Candore, G., Caruso, C., Di Bona, D. & Duro, G., 2018, In: Human Immunology. 79, p. 172-177 6 p.

  Research output: Contribution to journal › Article › peer-review

  • HLA Antigens
  • Systemic Lupus Erythematosus
  • Ligands
  • KIR Receptors
  • Taurine
  8 Citations (Scopus)

• Immune-inflammatory responses in the elderly: An update

  Accardi, G., Caruso, C., Accardi, G. & Caruso, C., 2018, In: IMMUNITY & AGEING. 15, 4 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Elderly
  23 Citations (Scopus)

• Immunosenescence and its hallmarks: How to oppose aging strategically? A review of potential options for therapeutic intervention

  Candore, G., Ligotti, M. E., Accardi, G., Caruso, C., Aiello, A., Gambino, C. M., Davinelli, S., Farzaneh, F. & Zareian, N., 2019, In: Frontiers in Immunology. 10, 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunosenescence
  • Nutrients
  • Vaccination
  • Interleukin-7
  • Immunomodulation
  52 Citations (Scopus)

• Mediterranean nutraceutical foods: Strategy to improve vascular ageing

  Caruso, C., Virruso, C., Gambino, C. M., Candore, G., Aiello, A. & Accardi, G., 2016, In: Mechanisms of Ageing and Development. 159, p. 63-70 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary Supplements
  • Food
  • Blood Vessels
  • Endothelial Progenitor Cells
  • Inflammation
  16 Citations (Scopus)

• Nutraceutical effects of table green olives: A pilot study with Nocellara del Belice olives

  Gambino, C. M., Accardi, G., Caruso, C., Candore, G., Aiello, A., Gargano, V., Marineo, S., Zinellu, A., Vesco, G., Caracappa, S., Carru, C., Vesco, G., Zarcone, M., Marineo, S., Caracappa, S. & Gargano, V., 2016, In: IMMUNITY & AGEING. 13

  Research output: Contribution to journal › Article › peer-review

  • Olea
  • Dietary Supplements
  • Food
  • Olive Oil
  • Lactobacillus
  16 Citations (Scopus)

• Nutrigerontology: A key for achieving successful ageing and longevity

  Candore, G., Caruso, C., Aiello, A., Accardi, G., Vasto, S., Vasto, S., Carruba, G., Davinelli, S., Scapagnini, G., Passarino, G. & Carruba, G., 2016, In: IMMUNITY & AGEING. 13, 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Longevity
  • Nutrients
  • Functional Food
  • Food
  • Dietary Supplements
  26 Citations (Scopus)

• Obesità, Microbiota e Aging

  Caruso, C., Aiello, A. & Accardi, G., 2016, La Medicina dell'Aging e dell'Anti-aging. p. 251-265 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian

  Ligotti, M. E., Ciaccio, M., Caruso, C., Aiello, A., Accardi, G., Vasto, S., Candore, G., Gambino, C. M., De Vivo, I., Cammarata, G., Carru, C., Cammarata, G., Caldarella, R. & Aprile, S., 2020, In: Aging clinical and experimental research. 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over
  • Longevity
  • Pathology

• Role of Immunogenetics in the Outcome of HCMV Infection: Implications for Ageing

  Accardi, G., Ligotti, M. E., Caruso, C., Gambino, C. M., Candore, G., Colomba, C., Aiello, A., Pandey, J. P., Bona, D. D., Bona, D. D., Duro, G., Di Bona, D. & Duro, G., 2019, In: International Journal of Molecular Sciences. 20, p. 00-00 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunogenetics
  • infectious diseases
  • Viruses
  • Cytomegalovirus Infections
  • viruses
  7 Citations (Scopus)

• Sicilian centenarian offspring are more resistant to immune ageing

  Aiello, A., Gambino, C. M., Accardi, G., Caruso, C., Bulati, M., Rubino, G., Gervasi, F. & Aprile, S., 2019, In: Aging clinical and experimental research. 31, p. 125-133 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over
  • Elderly
  • Mucosal-Associated Invariant T Cells
  • Immunosenescence
  • T-Lymphocytes
  11 Citations (Scopus)

• Slow-Ageing Diets

  Accardi, G., Caruso, C. & Aiello, A., 2019, Slow-Ageing Diets. 9 p. (Encyclopedia of Gerontology and Population Aging).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Healthy Aging
  • Eating
  • Diet
  • Vegetables
  • Fruit

• Targeting aging with functional food: Pasta with opuntia single-arm pilot study

  Candore, G., Di Miceli, G., Caruso, C., Accardi, G., Aiello, A., Ruisi, P., Gambino, C. M., Vasto, S., Nicosia, A., Zinellu, A., Di Bona, D., Carru, C. & Nicosia, A., 2018, In: Rejuvenation Research. 21, p. 249-256 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Opuntia
  • Functional Food
  • Antioxidants
  • Anti-Inflammatory Agents
  • Cactaceae
  6 Citations (Scopus)

• Taste receptor polymorphisms and longevity: a systematic review and meta-analysis

  Ligotti, M. E., Caruso, C., Accardi, G., Candore, G., Aiello, A., Malovini, A., Ferrario, A., Di Bona, D., Maciag, A., Puca, A. A. & Di Bona, D., 2020, In: Aging clinical and experimental research. 9 p.

  Research output: Contribution to journal › Article › peer-review

• Taste receptors, innate immunity and longevity: the case of TAS2R16 gene

  Caruso, C., Candore, G., Aiello, A., Accardi, G., Ligotti, M. E., Bellazzi, R., Malovini, A., Villa, F., Bellazzi, R., Maciag, A. & Puca, A. A., 2019, In: IMMUNITY & AGEING. 16

  Research output: Contribution to journal › Article › peer-review

  • Innate Immunity
  • Longevity
  • Genes
  • Population
  • Italy
  5 Citations (Scopus)

• The immunoglobulin γ marker 17 allotype and KIR/HLA genes prevent the development of chronic hepatitis B in humans

  Candore, G., Colomba, C., Caruso, C., Ligotti, M. E., Aiello, A., Accardi, G., Pandey, J. P., Bilancia, M., Di Bona, D., Macchia, L., Duro, G. & Rizzo, S., 2020, In: Immunology. p. 178-182 5 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Chronic Hepatitis B
  • HLA Antigens
  • Immunoglobulins
  • Hepatitis B

• The Phenotypic Characterization of the Cammalleri Sisters, an Example of Exceptional Longevity

  Aiello, A., Accardi, G., Candore, G., Vasto, S., Caruso, C., Gambino, C. M., Ciaccio, M. & Ligotti, M. E., 2020, In: Rejuvenation Research.

  Research output: Contribution to journal › Article › peer-review

  • Siblings
  • Longevity
  • Aged, 80 and over
  • Epigenomics
  • Molecular Biology

• The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs)

  Caruso, C., Cristaldi, L., Aiello, A., Di Gaudio, F., Cancemi, P., Accardi, G., Ciaccio, M., Candore, G., Vasto, S., Vasto, S., Siino, V., Cristaldi, L. & Caldarella, R., 2020, In: Mediators of Inflammation. 2020, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9
  • Matrix Metalloproteinases
  • Longevity
  • Antioxidants

• The signature of longevity in Sicily

  Scola, L., Aiello, A., Candore, G., Gambino, C. M., Vasto, S., Bulati, M., Accardi, G., Cristaldi, L., Caruso, C., Vasto, S., Cristaldi, Duro, G. & Duro, G., 2018, In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS. 32, p. 9-13 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Sicily
  • Aged, 80 and over
  • Longevity
  • Economic Status
  • Epigenomics
  1 Citation (Scopus)

• Translation of Basic Research into Clinics: Killer Immunoglobulin-like Receptors Genes in Autoimmune and Infectious Diseases

  Caruso, C., Colomba, C., Gambino, C. M., Ligotti, M. E., Aiello, A., Candore, G., Accardi, G., Di Bona, D., Duro, G., Di Bona, D. & Duro, G., 2018, In: CURRENT PHARMACEUTICAL DESIGN. 24, p. 3113-3122 10 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Autoimmune Diseases
  • Communicable Diseases
  • Genes
  • HLA Antigens
  5 Citations (Scopus)

• Uncoupling Protein 2 as genetic risk factor for systemic lupus erythematosus: association with malondialdehyde levels and intima media thickness

  Caruso, C., Aiello, A., Gambino, C. M., Candore, G., Gioia, B. G., Accardi, G., Ciaccio, M., Guggino, G. & Rizzo, S., 2020, In: Minerva Cardioangiologica. 68, p. 609-618 10 p.

  Research output: Contribution to journal › Article › peer-review