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• Aging successfully: The role of genetics and environment in the era of the aging-boom. potential therapeutic implications

  Accardi, G. & Aiello, A., 2019, In: CURRENT PHARMACEUTICAL DESIGN. 25, p. 4131-4132 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Longevity
  • Healthy Aging
  • Aptitude
  • Health Services Accessibility
  • Population

• Association between γ marker, human leucocyte antigens and killer immunoglobulin-like receptors and the natural course of human cytomegalovirus infection: a pilot study performed in a Sicilian population

  Bilancia, M.; Macchia, L.; Pandey, J., 2017, In: Immunology. 153, p. 523-531 9 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Cytomegalovirus Infections
  • HLA Antigens
  • Population
  • Cytomegalovirus
  9 Citations (Scopus)

• Beta-glucans and cancer: The influence of inflammation and gut peptide

  Baldassano, S., Accardi, G., Vasto, S. & Vasto, S., 2017, In: European Journal of Medicinal Chemistry. 142, p. 486-492 7 p.

  Research output: Contribution to journal › Article › peer-review

  • beta-Glucans
  • Glucans
  • Fortified Food
  • Peptides
  • Inflammation
  19 Citations (Scopus)

• Bioimpedance: a new approach for studyinglongevity

  Accardi, G., Vasto, S., Aiello, A. & Caruso, C., 2017, p. 67-78. 12 p.

  Research output: Contribution to conference › Other › peer-review

• Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing

  Caruso, C., Accardi, G., Puca, A. A., Villa, F. & Spinelli, C., 2017, In: Mechanisms of Ageing and Development. [Epub ahead of print], p. - 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Healthy Aging
  • Aged, 80 and over
  • Epigenomics
  • Longevity
  • Chromatin
  19 Citations (Scopus)

• Chance and Causality in Ageing and Longevity

  Vasto, S., Caruso, C., Accardi, G. & Aiello, A., 2019, Centenarians. An Example of Positive Biology.. p. 1-21 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • causality
  • life-span
  • statistician
  • joint venture
  • life sciences

• Clinical course and genetic susceptibility of primary biliary cirrhosis: Analysis of a prospective cohort

  Accardi, G., Grimaudo, S., Almasio, P. L., Caruso, C., Craxi, A., Licata, A., Costantino, A., Macaluso, F. S., Maida, M. F. & Alessi, N., 2016, In: Hepatitis Monthly. 16

  Research output: Contribution to journal › Article › peer-review

  • Biliary Liver Cirrhosis
  • Genetic Predisposition to Disease
  • HLA-DRB1*07 antigen
  • HLA-DRB1 Chains
  • Disease Progression
  3 Citations (Scopus)

• Dietary inflammatory index and cancer risk in the elderly: A pooled-analysis of Italian case-control studies

  Caruso, C., Accardi, G., Shivappa, N., Di Maso, M., La Vecchia, C., Polesel, J., Fratino, L., Libra, M., Serraino, D., Montella, M. & Hébert, J. R., 2019, In: Nutrition. 63-64, p. 205-210 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Case-Control Studies
  • Elderly
  • Neoplasms
  • Endometrium
  • Italy
  7 Citations (Scopus)

• Dietary supplements as surrogate of Mediterranean Diet in healthy smoking subjects

  Caruso, C., Candore, G., Di Gaudio, F., Rizzo, C. M., Barera, A., Vasto, S., Indelicato, S., Monastero, R., Accardi, G., Aiello, A., Italiano, E., Di Gaudio, F., Caruso, C., Vasto, S., Indelicato, S. & Galimberti, D., 2017, In: Rejuvenation Research. p. 37-43 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mediterranean Diet
  • Dietary Supplements
  • Piper nigrum
  • Antioxidants
  • Oxidative Stress
  2 Citations (Scopus)

• Dietary Supplements as Surrogate of Mediterranean Diet in Healthy Smoking Subjects

  Caruso, C., Candore, G., Di Gaudio, F., Rizzo, C. M., Barera, A., Vasto, S., Indelicato, S., Monastero, R., Accardi, G., Aiello, A. & Galimberti, D.; Italiano, E., 2017, In: Rejuvenation Research. p. - 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mediterranean Diet
  • Dietary Supplements
  • Piper nigrum
  • Antioxidants
  • Oxidative Stress

• Effects of nutraceuticals of Mediterranean diet on aging and longevity

  Caruso, C., Candore, G., Aiello, A. & Accardi, G., 2020, The Mediterranean Diet -2nd Edition- An Evidence-Based Approach. 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Mediterranean diet
  • functional foods
  • bioactive compounds
  • glycemic index
  • animal proteins

• From cellular senescence to age-associated diseases:miRNAs as tools and targets for healthy ageing

  Caruso, C. & Accardi, G., 2017, p. 27-37. 11 p.

  Research output: Contribution to conference › Other › peer-review

• Genetic Signatures of Centenarians: Implications for Achieving Successful Aging

  Caruso, C., Accardi, G., Aiello, A., Ciaglia, E., Cattaneo, M., Puca, A. & Cattaneo, M., 2019, In: CURRENT PHARMACEUTICAL DESIGN. 25, p. 4133-4138 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over
  • Longevity
  • Alleles
  • Medical Economics
  • Multifactorial Inheritance
  5 Citations (Scopus)

• Genotypic and phenotypic aspects of longevity: results from a Sicilian survey and implication for the prevention and the treatment of age-related diseases

  Mazzucco, W., Caruso, C., Cristaldi, L., Vasto, S., Gambino, C. M., Aiello, A., Candore, G., Accardi, G., Ligotti, M. E., Vasto, S., Cusimano, R., Bona, D. D., Galimberti, D., Cristaldi, L., Bona, D. D., Duro, G., Caruso, C., Di Bona, D., Duro, G., Cusimano, R. & 1 others, Aprile, S., 2019, In: CURRENT PHARMACEUTICAL DESIGN. 25, p. 228-235 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Longevity
  • Life Style
  • Sicily
  • Frailty
  • Translational Medical Research
  7 Citations (Scopus)

• HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute ischemic stroke

  Pecoraro, R., Di Raimondo, D., Aiello, A., Casuccio, A., Tuttolomondo, A., Pinto, A., Accardi, G., Maida, C. D., Della Corte, V., Simonetta, I., Caruso, C., Arnao, V., Pecoraro, R., Squatrito, R., Di Bona, D., Di Bona, D. & Clemente, G., 2019, In: Journal of Neuroinflammation. 16, 15 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • HLA Antigens
  • Stroke
  • Genes
  • Alleles
  7 Citations (Scopus)

• Immunosenescence and its hallmarks: How to oppose aging strategically? A review of potential options for therapeutic intervention

  Gambino, C. M., Candore, G., Ligotti, M. E., Accardi, G., Caruso, C., Aiello, A., Davinelli, S., Farzaneh, F. & Zareian, N., 2019, In: Frontiers in Immunology. 10, 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunosenescence
  • Nutrients
  • Vaccination
  • Interleukin-7
  • Immunomodulation
  50 Citations (Scopus)

• KIR2DL3 and the KIR ligand groups HLA-A-Bw4 and HLA-C2 predict the outcome of hepatitis B virus infection.

  Giannitrapani, L., Cascio, A., Colomba, C., Rubino, R., Tuttolomondo, A., Aiello, A., Caruso, C., Montalto, G., Candore, G., Di Lorenzo, G., Accardi, G., Rizzo, S., Bilancia, M., Di Bona, D., Macchia, Duro, G., Caiaffa, Candore, Rizzo, S. & Caruso, C., 2017, In: Journal of Viral Hepatitis. 24, p. 768-775 8 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • HLA Antigens
  • Hepatitis B
  • Ligands
  • Chronic Hepatitis B
  21 Citations (Scopus)

• Mediterranean Diet as a tool for achievingsuccessful ageing

  Accardi, G., Caruso, C. & Aiello, A., 2017, In: Aesthetic Medicine. 3, 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mediterranean Diet
  • Glycemic Index
  • Functional Food
  • Healthy Lifestyle
  • Dietary Supplements

• Mediterranean nutraceutical foods: Strategy to improve vascular ageing

  Caruso, C., Virruso, C., Gambino, C. M., Candore, G., Aiello, A. & Accardi, G., 2016, In: Mechanisms of Ageing and Development. 159, p. 63-70 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary Supplements
  • Food
  • Blood Vessels
  • Endothelial Progenitor Cells
  • Inflammation
  16 Citations (Scopus)

• Nutraceutical effects of table green olives: A pilot study with Nocellara del Belice olives

  Candore, G., Gambino, C. M., Accardi, G., Caruso, C., Aiello, A., Gargano, V., Marineo, S., Zinellu, A., Vesco, G., Caracappa, S., Carru, C., Vesco, G., Zarcone, M., Marineo, S., Caracappa, S. & Gargano, V., 2016, In: IMMUNITY & AGEING. 13

  Research output: Contribution to journal › Article › peer-review

  • Olea
  • Dietary Supplements
  • Food
  • Olive Oil
  • Lactobacillus
  16 Citations (Scopus)

• Nutrient sensing pathways as therapeutic targets for healthy ageing

  Gambino, C. M., Caruso, C., Virruso, C., Accardi, G., Mirisola, M. G., Aiello, A., Taormina, G. & Candore, G., 2017, In: Expert Opinion on Therapeutic Targets. 21, p. 371-380 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Healthy Aging
  • Nutrients
  • Aging of materials
  • Imagination
  • Dreams
  11 Citations (Scopus)

• Nutrigerontology: A key for achieving successful ageing and longevity

  Caruso, C., Candore, G., Aiello, A., Accardi, G., Vasto, S., Vasto, S., Carruba, G., Davinelli, S., Scapagnini, G., Passarino, G. & Carruba, G., 2016, In: IMMUNITY & AGEING. 13

  Research output: Contribution to journal › Article › peer-review

  • Longevity
  • Nutrients
  • Functional Food
  • Food
  • Dietary Supplements
  26 Citations (Scopus)

• Obesità, Microbiota e Aging

  Caruso, C., Aiello, A. & Accardi, G., 2016, La Medicina dell'Aging e dell'Anti-aging. p. 251-265 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Proceedings of the Symposium “Updates inPathobiology: Causality and Chance inAgeing, Age-related diseases and Longevity”

  Accardi, G. & Caruso, C., 2017, UniPaPress. 188 p.

  Research output: Book/Report › Other report

  • physicians
  • biotechnology
  • medicine

• Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian

  Candore, G., Gambino, C. M., Ligotti, M. E., Ciaccio, M., Caruso, C., Aiello, A., Accardi, G., Vasto, S., De Vivo, I., Cammarata, G., Carru, C., Cammarata, G., Caldarella, R. & Aprile, S., 2020, In: Aging clinical and experimental research. 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over
  • Longevity
  • Pathology

• Role of Immunogenetics in the Outcome of HCMV Infection: Implications for Ageing

  Accardi, G., Ligotti, M. E., Caruso, C., Gambino, C. M., Candore, G., Colomba, C., Aiello, A., Pandey, J. P., Bona, D. D., Bona, D. D., Duro, G., Di Bona, D. & Duro, G., 2019, In: International Journal of Molecular Sciences. 20, p. 00-00 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunogenetics
  • infectious diseases
  • Viruses
  • Cytomegalovirus Infections
  • viruses
  7 Citations (Scopus)

• Sicilian centenarian offspring are more resistant to immune ageing

  Aiello, A., Gambino, C. M., Accardi, G., Caruso, C., Bulati, M., Rubino, G., Gervasi, F. & Aprile, S., 2019, In: Aging clinical and experimental research. 31, p. 125-133 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Aged, 80 and over
  • Elderly
  • Mucosal-Associated Invariant T Cells
  • Immunosenescence
  • T-Lymphocytes
  11 Citations (Scopus)

• Slow-Ageing Diets

  Accardi, G., Caruso, C. & Aiello, A., 2019, Slow-Ageing Diets. 9 p. (Encyclopedia of Gerontology and Population Aging).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Healthy Aging
  • Eating
  • Diet
  • Vegetables
  • Fruit

• Targeting Aging with Functional Food: Pasta with Opuntia Single-Arm Pilot Study

  Di Bona, D.; Carru, C.; Zinellu, A., 2017, In: Rejuvenation Research. p. - 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Opuntia
  • Functional Food
  • Antioxidants
  • Anti-Inflammatory Agents
  • Cactaceae

• Taste receptor polymorphisms and longevity: a systematic review and meta-analysis

  Candore, G., Ligotti, M. E., Caruso, C., Accardi, G., Aiello, A., Malovini, A., Ferrario, A., Di Bona, D., Maciag, A., Puca, A. A. & Di Bona, D., 2020, In: Aging clinical and experimental research. 9 p.

  Research output: Contribution to journal › Article › peer-review

• Taste receptors, innate immunity and longevity: the case of TAS2R16 gene

  Caruso, C., Candore, G., Aiello, A., Accardi, G., Ligotti, M. E., Bellazzi, R., Malovini, A., Villa, F., Bellazzi, R., Maciag, A. & Puca, A. A., 2019, In: IMMUNITY & AGEING. 16

  Research output: Contribution to journal › Article › peer-review

  • Innate Immunity
  • Longevity
  • Genes
  • Population
  • Italy
  5 Citations (Scopus)

• The immunoglobulin γ marker 17 allotype and KIR/HLA genes prevent the development of chronic hepatitis B in humans

  Colomba, C., Candore, G., Caruso, C., Accardi, G., Aiello, A., Ligotti, M. E., Pandey, J. P., Bilancia, M., Di Bona, D., Macchia, L., Duro, G. & Rizzo, S., 2020, In: Immunology. p. 178-182 5 p.

  Research output: Contribution to journal › Article › peer-review

  • KIR Receptors
  • Chronic Hepatitis B
  • HLA Antigens
  • Immunoglobulins
  • Hepatitis B

• The importance of the interactions between KIRs andHLA ligands in the development of human autoimmuneand viral diseases

  Accardi, G., Gambino, C. M., Caruso, C., Candore, G., Aiello, A. & Di Bona, D., 2017, p. 67-78. 12 p.

  Research output: Contribution to conference › Other › peer-review

  • KIR Receptors
  • Human Development
  • Virus Diseases
  • Ligands
  • HLA Antigens

• The Phenotypic Characterization of the Cammalleri Sisters, an Example of Exceptional Longevity

  Aiello, A., Accardi, G., Candore, G., Vasto, S., Caruso, C., Gambino, C. M., Ciaccio, M. & Ligotti, M. E., 2020, In: Rejuvenation Research.

  Research output: Contribution to journal › Article › peer-review

  • Siblings
  • Longevity
  • Aged, 80 and over
  • Epigenomics
  • Molecular Biology

• The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs)

  Candore, G., Vasto, S., Caruso, C., Cristaldi, L., Di Gaudio, F., Aiello, A., Cancemi, P., Accardi, G., Ciaccio, M., Vasto, S., Siino, V., Cristaldi, L. & Caldarella, R., 2020, In: Mediators of Inflammation. 2020, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9
  • Matrix Metalloproteinases
  • Longevity
  • Antioxidants

• Uncoupling Protein 2 as genetic risk factor for systemic lupus erythematosus: association with malondialdehyde levels and intima media thickness

  Caruso, C., Aiello, A., Gambino, C. M., Candore, G., Gioia, B. G., Accardi, G., Ciaccio, M., Guggino, G. & Rizzo, S., 2020, In: Minerva Cardioangiologica. 68, p. 609-618 10 p.

  Research output: Contribution to journal › Article › peer-review

• Updates in Pathobiology: Causality and Chance in Ageing,Age-Related Diseases and Longevity

  Caruso, C. & Accardi, G., 2017, p. 13-23. 11 p.

  Research output: Contribution to conference › Other › peer-review