• 1866 Citations
  • 30 h-Index
20042019

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2019

An overview on chemical structures as ΔF508-CFTR correctors

Montalbano, A., Barraja, P., Spano', V., Carbone, A., Scudieri, P. & Galietta, L. J. V., 2019, In : European Journal of Medicinal Chemistry. 180, p. 430-448 19 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Furocoumarins as multi-target agents in the treatment of cystic fibrosis

Carbone, A., Spano', V., Barraja, P., Montalbano, A., Musante, I. & Galietta, L. J. V., 2019, In : European Journal of Medicinal Chemistry. 180, p. 283-290 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2 Citations (Scopus)
4 Citations (Scopus)
2018
12 Citations (Scopus)
5 Citations (Scopus)
2017
30 Citations (Scopus)
19 Citations (Scopus)
4 Citations (Scopus)
8 Citations (Scopus)
60 Citations (Scopus)

Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity

Cilibrasi, V., Cirrincione, G., Montalbano, A., Carbone, A., Cascioferro, S. M., Spano', V., Parrino, B., Giallombardo, D., Diana, P., Barraja, P., Doria, F., Frasson, I., Salvador, A., Freccero, M. & Richter, S. N., 2017, In : European Journal of Medicinal Chemistry. 128, p. 300-318 19 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
36 Citations (Scopus)
13 Citations (Scopus)
2016

[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors

Spano', V., Montalbano, A., Barraja, P., Parrino, B., Diana, P., Carbone, A., Cirrincione, G., Lopergolo, A., Cominetti, D., Pennati, M., Zuco, V. & Zaffaroni, N., 2016, In : European Journal of Medicinal Chemistry. 124, p. 840-851 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma

Montalbano, A., Cilibrasi, V., Cirrincione, G., Barraja, P., Diana, P., Parrino, B., Spano', V., Carbone, A., Lopergolo, A., Cominetti, D., Pennati, M., Zuco, V. & Zaffaroni, N., 2016, In : Journal of Medicinal Chemistry. 59, p. 7223-7238 16 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
9 Citations (Scopus)
11 Citations (Scopus)

Synthesis and antitumor activity of new thiazole nortopsentin analogs

Tesoriere, L., Cirrincione, G., Parrino, B., Montalbano, A., Carbone, A., Barraja, P., Diana, P., Cascioferro, S. M., Spano', V., Spanò, V., Parrino, B., Attanzio, A., Carbone, A., Cascioferro, S., Montalbano, A., Barraja, P., Cirrincione, G., Diana, P., Tesoriere, L. & Attanzio, A., 2016, In : Marine Drugs. 14, 18 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2015

3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity

Spano', V., Carbone, A., Barraja, P., Cirrincione, G., Di Vita, G., Tesoriere, L., Parrino, B., Livrea, M. A., Montalbano, A., Diana, P., Ciancimino, C., Spanò, V., Parrino, B., Attanzio, A., Ciancimino, C., Carbone, A., Di Vita, G., Montalbano, A., Barraja, P., Cirrincione, G. & 4 others, Diana, P., Tesoriere, L., Livrea, M. A. & Attanzio, A., 2015, In : Marine Drugs. 13, p. 1901-1924 24 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
37 Citations (Scopus)

Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer

Carbone, A., Cirrincione, G., Parrino, B., Diana, P., Montalbano, A., Spano', V., Barraja, P., Salvador, A., Brun, P., Brun, P. & Vedaldi, D., 2015, In : European Journal of Medicinal Chemistry. 102, p. 334-351 18 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
41 Citations (Scopus)
18 Citations (Scopus)

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action

Cirrincione, G., Carbone, A., Ciancimino, C., Parrino, B., Spano', V., Barraja, P., Diana, P., Montalbano, A., Pinato, O., Pennati, M., Folini, M., Sissi, C., Matyus, P., Zaffaroni, N., Balogh, B., Beretta, G. & Palumbo, M., 2015, In : European Journal of Medicinal Chemistry. 94, p. 149-162 14 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues

Parrino, B., Spano', V., Montalbano, A., Carbone, A., Barraja, P., Cirrincione, G., Diana, P., Lopergolo, A., Sbarra, Spanò, V., Parrino, B., Doldi, Carbone, A., Pennati, M., Montalbano, A., Barraja, P., Cirrincione, G., Diana, P. & Zaffaroni, N., 2014, In : Current Medicinal Chemistry. 21, p. 1654-1666 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitoticactivity

Cirrincione, G., Spano', V., Diana, P., Carbone, A., Barraja, P., Parrino, B., Montalbano, A., Salvador, A., Tisi, S., Primac, I., Primac, I., Brun, P., Brun, P., Castagliuolo, I., Vedaldi, D. & Issinger, O-G., 2014, In : European Journal of Medicinal Chemistry. 74, p. 340-357 18 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
11 Citations (Scopus)

‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles

Barraja, P., Diana, P., Montalbano, A., Carbone, A., Cirrincione, G., Spano', V., Parrino, B., Spanò, V., Parrino, B., Carbone, A., Montalbano, A., Barraja, P., Cirrincione, G., Diana, P. & Màtyus, P., 2014, In : Tetrahedron. 70, p. 7318-7321 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013

Convenient synthesis of pyrrolo[3,4-g]indazole

Carbone, A., Barraja, P., Cirrincione, G., Diana, P., Parrino, B., Montalbano, A., Spano', V., Spanò, V., Parrino, B., Carbone, A., Montalbano, A., Barraja, P., Cirrincione, G. & Diana, P., 2013, In : Tetrahedron. 69, p. 9839-9847 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues:Synthesis and Antitumor Activity in Peritoneal MesotheliomaExperimental Models

Spano', V., Montalbano, A., Carbone, A., Parrino, B., Cirrincione, G., Barraja, P., Diana, P., Lopergolo, A., Sbarra, S., Doldi, V., Pennati, M., De Cesare, M. & Zaffaroni, N., 2013, In : Journal of Medicinal Chemistry. 56, p. 7060-7072 13 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

Barraja, P., Parrino, B., Spano', V., Diana, P., Cirrincione, G., Carbone, A., Spanò, V., Fiebig, H-H., Parrino, B., Carbone, A., Barraja, P., Cirrincione, G., Diana, P., Maier, A. & Kelter, G., 2013, In : Marine Drugs. 11, p. 643-654 12 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Synthesis of [1,2]oxazolo[5,4-e]indazoles as antitumour agents

Barraja, P., Diana, P., Cirrincione, G., Giallombardo, D., Parrino, B., Montalbano, A., Spano', V., Carbone, A., Spanò, V., Parrino, B., Giallombardo, D., Carbone, A., Montalbano, A., Barraja, P., Cirrincione, G. & Diana, P., 2013, In : Tetrahedron. 69, p. 6474-6477 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Synthesis of the new oligopeptide pyrrole derivative isonetropsinand its one pyrrole unit analogue

Carbone, A., Montalbano, A., Spano', V., Cirrincione, G., Diana, P., Barraja, P., Parrino, B., Spanò, V., Parrino, B., Carbone, A., Montalbano, A., Barraja, P., Cirrincione, G. & Diana, P., 2013, In : Tetrahedron. 69, p. 2550-2554 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2012
24 Citations (Scopus)
24 Citations (Scopus)
2011
13 Citations (Scopus)

Pyrrolo[3,2-h]quinazolines as Photochemotherapeutic Agents

Montalbano, A., Diana, P., Cirrincione, G., Carbone, A., Barraja, P., Salvador, A., Tisi, S., Brun, P., Brun, P., Castagliuolo, I., Vedaldi, D. & Dall'Acqua, F., 2011, In : ChemMedChem. 6, p. 1238-1248 11 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents

Cirrincione, G., Diana, P., Barraja, P., Montalbano, A., Carbone, A., Salvador, A., Vedaldi, D., Dall'Acqua, F., Viola, G. & Basso, G., 2011, In : BIOORGANIC & MEDICINAL CHEMISTRY. 19, p. 2326-2341 16 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Synthesis and Antitumor Activity of 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-indoles and 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-7-azaindoles

Carbone, A., Diana, P., Barraja, P., Cirrincione, G., Montalbano, A., Parrino, B., Lopergolo, A., Pennati, M. & Zaffaroni, N., 2011, In : ChemMedChem. 6, p. 1300-1309 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
32 Citations (Scopus)

Synthesis of Triazenoazaindoles: a New Class of Triazenes with Antitumor Activity

Diana, P., Barraja, P., Cirrincione, G., Carbone, A., Parrino, B., Salvador, A., Brun, P., Brun, P., Castagliuolo, I., Vedaldi, D., Dall'Acqua, F. & Issinger, O. G., 2011, In : ChemMedChem. 6, p. 1291-1299 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2010
100 Citations (Scopus)

SYNTHESIS OF PYRROLO[3,2-H]QUINOLINONES WITH GOOD PHOTOCHEMOTHERAPEUTIC ACTIVITY AND NO DNA DAMAGE

Carbone, A., Barraja, P., Diana, P., Montalbano, A., Cirrincione, G., Salvador, A., Brun, P., Brun, P., Castagliuolo, I., Vedaldi, D., Palù, G., Dall'Acqua, F. & Caracausi, L., 2010, In : BIOORGANIC & MEDICINAL CHEMISTRY. 18, p. 4830-4843 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2009

Pyrano[2,3-e]isoindol-2-ones, new angelicin heteroanalogues

Carbone, A., Diana, P., Spano', V., Barraja, P., Cirrincione, G., Salvador, A., Vedaldi, D., Dall'Acqua, F. & Viola, G., 2009, In : BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 19, p. 1711-1714 4 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)